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Discovery Medicine • February 2010<br />

Vaccines and autoimmune diseases of the adult<br />

Author information<br />

Orbach H1, Agmon-Levin N, Zandman-Goddard G.<br />

Department of Medicine B<br />

Wolfson Medical Center<br />

Holon, Israel<br />

Abstract<br />

Infectious agents contribute to the environmental factors involved in the<br />

development of autoimmune diseases possibly through molecular mimicry<br />

mechanisms. Hence, it is feasible that vaccinations may also contribute to<br />

the mosaic of autoimmunity. Evidence for the association of vaccinations and<br />

the development of these diseases is presented in this review. Infrequently reported<br />

post-vaccination autoimmune diseases include systemic lupus erythematosus,<br />

rheumatoid arthritis, inflammatory myopathies, multiple sclerosis,<br />

Guillain-Barré syndrome, and vasculitis. In addition, we will discuss macrophagic<br />

myofasciitis, aluminum containing vaccines, and the recent evidence<br />

for autoimmunity following the use of human papillomavirus vaccine.<br />

http://www.ncbi.nlm.nih.gov/pubmed/20193633<br />

“Hence, it is feasible that vaccinations may also contribute<br />

to the mosaic of autoimmunity. Evidence for the association of<br />

vaccinations and the development of these diseases is presented in<br />

this review. In addition, we will discuss macrophagic myofasciitis,<br />

aluminum containing vaccines, and the recent evidence for<br />

autoimmunity following the use of human papillomavirus vaccine.”<br />

Full Report<br />

http://www.discoverymedicine.com/Hedi-Orbach/2010/02/04/vaccines-and-autoimmune-diseases-of-the-adult/

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