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Journal Of Pediatrics • May 2000<br />

Iatrogenic exposure to mercury<br />

after hepatitis B vaccination in preterm infants<br />

Author information<br />

Stajich GV1, Lopez GP, Harry SW, Sexson WR.<br />

Mercer University<br />

Southern School of Pharmacy<br />

Atlanta, Georgia 30341, USA<br />

Abstract<br />

Thimerosal, a derivative of mercury, is used as a preservative in hepatitis<br />

B vaccines. We measured total mercury levels before and after the administration<br />

of this vaccine in 15 preterm and 5 term infants. Comparison of<br />

pre- and post-vaccination mercury levels showed a significant increase in<br />

both preterm and term infants after vaccination. Additionally, post-vaccination<br />

mercury levels were significantly higher in preterm infants as compared<br />

with term infants. Because mercury is known to be a potential neurotoxin<br />

to infants, further study of its pharmacodynamics is warranted.<br />

“Comparison of pre- and post-vaccination<br />

mercury levels showed a significant increase<br />

in both preterm and term infants after vaccination.”<br />

http://www.ncbi.nlm.nih.gov/pubmed/10802503

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