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Science • May 1973<br />

Brain aluminum distribution<br />

in Alzheimer’s disease and<br />

experimental neurofibrillary degeneration<br />

Crapper DR, Krishnan SS, Dalton AJ.<br />

Abstract<br />

Neurofibrillary degeneration is an important pathological finding<br />

in senile and presenile dementia of the Alzheimer type. Experimentally,<br />

aluminum induces neurofibrillary degeneration in neurons<br />

of higher mammals. Aluminum concentrations approaching<br />

those used experimentally have been found in some regions of the<br />

brains of patients with Alzheimer’s disease.<br />

“Experimentally,<br />

aluminum induces neurofibrillary degeneration<br />

in neurons of higher mammals.”<br />

http://www.ncbi.nlm.nih.gov/pubmed/4735595

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