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Pharma Turkey Dergisi Eylül – Ekim 2017 Sayısı

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New generation sequencing (next generation<br />

Sequencing) of cancerous<br />

and normal cells with the genetic<br />

map analysis methods able to determine<br />

a so-called very quickly and at a<br />

lower cost compared with the not the<br />

same. In a foreseeable future, we will<br />

start by removing the genetic map of<br />

the cancer cell in all of our patients<br />

and we will determine the treatment<br />

method to follow. We recommend<br />

common treatment approaches for<br />

patients with certain genetic characteristics,<br />

even if each individual has<br />

no specific treatment. Targeted treatment<br />

costs are extremely high. Participation<br />

in scientific studies needs<br />

to be increased in order for these<br />

treatments to become widespread in<br />

our country. I need to give expensive<br />

treatment to the patient group who<br />

will really benefit. Here we need to<br />

break down the concept of 'guinea<br />

pigs'. The circumstances in which a<br />

patient is treated in optimum conditions<br />

provide scientific research. There<br />

are strict controls here. Every stage<br />

is passed through the eye. The illness<br />

treated within the scope of the research<br />

with folk expression is regarded<br />

as 'hand baby rose baby'. Do not<br />

hesitate to join our patients in these<br />

scientific investigations, each stage of<br />

which is strictly controlled. But in this<br />

way they are able to get free access<br />

to costly treatment options. They are<br />

both free to use the treatment, and<br />

they have a chance to go through<br />

a much more rigorous care than a<br />

standard patient.”<br />

<strong>Turkey</strong> is preparing to test the first<br />

indigenous living medicine in cancer<br />

treatment ...<br />

<strong>Turkey</strong>'s 'first domestic leather production'<br />

with the invention, one of the<br />

world's prestigious medical awards<br />

US Plastic and Reconstructive Surgery<br />

Association's awarded the prize<br />

of 'Best Experimental Research' Prof.<br />

Dr. Ercument Ovali was among the<br />

congress speakers. Professor Dr. Ercument<br />

Ovali, <strong>Turkey</strong>'s first genetically<br />

modified cell therapy in the 4th<br />

Hematological Oncology Congress<br />

announced for the first time. Professor<br />

participating in the Congress of<br />

the drug treatment to live in <strong>Turkey</strong><br />

wants to support the expression of<br />

Professor. Dr. Ercument Ovalı said,<br />

"Because you have to prepare the<br />

method of treatment in the laboratory<br />

or to show that it works on animals<br />

alone does not have any importance.<br />

This treatment method should be<br />

rapidly tested in <strong>Turkey</strong> with a clinical<br />

trial. Instead of seeing themselves<br />

as guinea pigs, they need to trust the<br />

team to be able to hold on to life and<br />

to keep others alive. This will bring<br />

us two things. <strong>Turkey</strong> will have tested<br />

the native genetically modified cell<br />

as it produces and many people will<br />

change their lives.”<br />

Living the life expectancy in some<br />

types of cancer drugs can be extended<br />

to 3 years 3 months ...<br />

Exampling Made in the USA CR-T cell<br />

the treatment that Prof. Dr. Ercument<br />

Ovalı said, "An acute lymphoblastic<br />

leukemia in children's life<br />

expectancy is resistant to any kind<br />

of treatment is less than 6 months,<br />

or even the average is around 3<br />

months. With today's technology, you<br />

have no other chance. But with these<br />

living medicines, 95 percent of these<br />

children can achieve 3 year survival.<br />

This is a revolution. But this is not<br />

a treatment you can take from your<br />

pharmacy. They have complications. A<br />

method of treatment of hematopoietic<br />

stem cell transplant teams who<br />

can apply. That's why conventions<br />

like this allow us to build teams. We<br />

will train each other. Because the<br />

job does not end with the production<br />

in the lab. Clinical results are very<br />

important. Thank you for bringing<br />

us together for the Hematological<br />

Oncology Society. If there is no setback,<br />

we aim to start phase 1 studies<br />

in January 2018. Leukemia in three<br />

separate diseases, but will work in lymphoma<br />

patients and MyOle. We aim<br />

to practice on a total of 27 patients<br />

with 9 patients. I need the support of<br />

our doctors for this.”<br />

Turkish patients will be able to benefit<br />

much less in <strong>Turkey</strong> with half a<br />

trillion worth of treatment ...<br />

CR-T cell, a process which began approach<br />

to cost half a trillion last year<br />

at 35 centers in the United States. For<br />

many years, bone marrow transplants<br />

have shown scientists that the power<br />

to destroy a self-made cancer is<br />

less than that of any other human<br />

being. Living medicines have caused<br />

a significant change in this understanding<br />

and have begun to be used by<br />

subjecting one's own cell to genetic<br />

alteration. Thus, it began to fight cancer,<br />

as if the person's own immune<br />

cell was a micro-battle. If this technology<br />

is established in <strong>Turkey</strong> under the<br />

leadership of Turkish scientists, the<br />

cost will be much less and acceptable.<br />

The costs of treatment will go from<br />

one state to another and remain in<br />

our country.<br />

<strong>Pharma</strong><br />

September- October ‘17 15

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