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4.4.3 Trscc.temeDf!<br />
4.4,3.1 I.oo ir ptr.ma<br />
An.tysi! or @i.@ ror iron mn@nlorjon in dsm ofnlte .,& Sivd in TaU.<br />
57 showed no.f.cr of .6!renr rnd f€ding pqiod, ,fh€ mn @@nr€lion in ptcma<br />
ha b€n dcpicr.d in Tsblc 58_ Th. cufts l|irs obhined e p@n@ !n aprodix 14.<br />
The @nccnh.tioh ot iu h ptass ot @le ob fed NdFeED1A with .itho<br />
$ue orzirc supplhenr.d dier{Tr dd T6) wfoundioe non,.snintudy highd<br />
wh.tr conp.rd wnh conrol bur thc oncentrotion ofroo o.cNsed non sre,irirrntty<br />
when .lcmentll ion wls siven wid zitu eurc.s, TIE dqrnrion ot io. in pl6D. of<br />
mr.6b thouah difrercd non li$ititu y bur lhe ruulls indiqrcl dur.lqqbl iM<br />
inlc@t.d neg.rivctywirh zinc eu@s_,nr.rc ws a non rignifi.st in@& of 16 %ol<br />
i@ @nen|rafion in ptM. of n.tc ds wlM clmeitrt iM (.r.r) qs Ci6 ltorc.<br />
4.4.3.2I.on In tiv€.<br />
The tuslysis of veire fo. d. onatrdid of imn in lisr oa rh. mdc ..|! hs<br />
b€.n india€d h T.btc 59, Fqji.g pdiod non significstty sff.ded iDn co&shdlioD<br />
in liv( of nal. rars Howvc( rr.llh€nts .fIEr ws tound io be sjanifiMi rdeeraE<br />
.fi6t o, lccdnrg p.rio& ond ire.lnols @ ot$ found to b€ Don rignificani ,or liver ion<br />
conen.mrion. Ir h .vid.nt fon Tabt. 60 rtet tre odimh onq|Iarion of ien in<br />
liw oa rhc ml. 6L w6 found for l6n&nt Tr dd T, snd uE hnamum @nqhrior<br />
of 'rcn in lieer wos uber\eo ror rErh€nr t,. .t he Natc[DlA .ddeo aton. in whotc<br />
!h@t tlor (TD tud eteDenral i,on rvirh ZnSo. (T, Fd!@d rinjtd cfleLs tor i()n<br />
@n@tEtion in Dalc d's tivc., NA Fe EDTA add.d qlorc nr whot. qtrql flour<br />
EUlt d h b.(er Er..tion of imn in livq €mp(sd wtrh dd6d iq llorc bdr*<br />
N! F.EDTA i. tlDughr .o b. hig y !i@v! .bl. lnd imn in n i, ch.lst d ,irr, EDTA, .<br />
ooh'.onry us.d rood oddtriv. *hioh prevcnr th. ion Fofl b€itrs bound wirh phr{ic &id.<br />
'rh& linding e h tine with lhe oa vnei ( l99t rno i.rd lxd N.FeEDT i. bdc.<br />
absodcd ed not eNitiv. Io muy tood tor itrhibilo$ it @hpoRrt with otlB ion<br />
I.on md zinc in 3rt mlio w.E fed ro fte matc Br! in rc.thent Tr, As UF<br />
mnan|[lbn of ion in T, ws sanihr b ,t, m in|.@rio @ll€d posrdadng dor<br />
ZnSO. augn rd lhe absorption of non in t,. CoRer .r z/, I I o8r) Rponcn lhar drE