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L./f*A tuf ac.-lL,;l u sV})

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delled th.l nelaronin has a lt'ybid tutrction suppressins rclion,ju,| dE opposit. !o th.<br />

&lions ofzinc. When zinc k adNn $er€d along with nel|tonin. il3 rhyroid funclion<br />

suplJGsion is dnnirrirhcd<br />

2.5.3 Iror rnd zirc corceorr.riotr ltr dita.r.nr Drs,tr,.<br />

Ka.s dral. (1977)conducEd m cxpedncnr wirhnrsro deicnhire rlE efie6 on<br />

rhe ris!. concentrorions ofznt tre, cu, ond Mg or |cedins vffious.nbu sotiiic. tl'e<br />

r uts werc lan-lixl otre ot rlB fotlowhgdie6 tor tbur w.etjr.Diel A, a zi.cncficient di.t;<br />

! di.r conkining the r@onhdcd amoutrl ofzinc rLtiel A ttu! 55 mirro8.,n ofnnL per<br />

8@ ol diet), or dier A plus t50 microssN zinc per c6m ofdier. coNcnrblioB of<br />

rris elcmcnls ir v.rious tissres wee ddtsmnrd by oromic rbsorprion lpectmmky<br />

0n.( w.l dig*rion. llc€diDg the 6ts zinc-supptemared di.b Esuhed in intraqt zitu in<br />

blood, h@1, tidn y, drl livq, !d ! mar(el dec@ of ion in kidncy rnd ritcr<br />

ConqtBrions ol tlE orh.rrm clcm.nrswc u.chrnecd in alltissu6.<br />

FaiMolh€Fldit nnd Wrishr (1984) ne$ued non .erenliun trd iG subs€qcnr<br />

dislribulion fron 3 s 59I€ eftinsiqllyJrbeted whole wlHt flour in rars givcn ! bq (8<br />

Nicogr.hs [./s)- or hish (566 ugfe/g-Fe diet duriog t]E Fcvious 3 d. Th@ wss no<br />

dilT@ne in disribution of.be.b.d 59F. in rhe tGru€r .rmin.d lor Fr erdin.d in Ea<br />

sircn th€ lo*, D.dium, orhi!h-!i di.rs lor I d.<br />

Laetr lnd Sandn0n (1992) ovsluarcd (isue ood or8or d€position od btood<br />

l).mneleN !s indices of Nne6l trd tr&e .leme rbsrpLioh in rar5, Thc .berprion of<br />

el.n.nrs w6 qutrtili.d in r.Lrion !o nitro8.n rcranion, b, c@adcri.g rN *eighr g3in<br />

and rcP tistlc ayndresis, A dpcs..d msl diet M! $pplied wnh tu€. lelcls ofcalciunr,<br />

t*o hveh olzinc,.nd two lcvclsofqtpcrnr a leloridldosiSn. In e.neral, m inc@*<br />

in di.tar) nin.El content irtc€asd lhc reloLivc aberprion, wnid i[ tun, nEftse! rhc<br />

lissue depositioo pbgressively. Srriakd nr$lc, howwer, diJ nor cpond lo cirher atr<br />

hcrcsql culciun or zirc $pply. flrdrBnoF, inqged caloium abso{,iior c.lscd a<br />

dcpBsionofth. f ctionll phosphorus otrd masn$ium €trrcnt of f.mft bob$. fhe ion<br />

conle* ofrissuc wss, in Bencnl, i|!e6ely poponioodl Lo zinc dberption dd sho*ed 0<br />

l€ndency ro be dn.cll' propo i6tr,lro coppclbsorprion. lh.2nr. bvelnr dsn'es vas, i[<br />

! similtr wy, invcc.ly corelared lo m.ssurcd colcium absorption. Ir conclusion,<br />

26

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