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Nikolaus 1999 plus ESD<br />

Methods Year: 1999<br />

Location: Heidelberg, Germany (University Hospital)<br />

Team/ward?: ward<br />

Timing: acute (within 48 hours)<br />

Trial methodology: randomised controlled trial with 2 intervention arms - <strong>geriatric</strong><br />

<strong>assessment</strong> and management with early supported discharge (home intervention team)<br />

or <strong>geriatric</strong> <strong>assessment</strong> alone versus usual care<br />

Participants Numbers (<strong>to</strong>tal): 545<br />

Mean age: 81<br />

Male:female ratio: unclear<br />

Inclusion criteria: elderly patients with multiple chronic conditions or functional deterioration<br />

or who were at risk of nursing home placement<br />

Exclusion criteria: terminal illness, severe dementia, patients who lived > 15 km away<br />

Patient selection criteria: selected<br />

Patient selection criteria details: as above<br />

Interventions Team members: senior <strong>geriatric</strong>ian, specialist nurses, physiotherapists, occupational therapists,<br />

social workers. (The home intervention team consisted of 3 nurses, a physiotherapist,<br />

an occupational therapist, a social worker and secretarial support)<br />

Team organisation: comprehensive <strong>assessment</strong>, standardised <strong>assessment</strong> <strong>to</strong>ols, outpatient<br />

follow up (HIT team)<br />

Outcomes Outcomes: Institutionalisation, readmission, costs, length of stay, perceived health status,<br />

dependence<br />

Trial conclusions: comprehensive <strong>geriatric</strong> <strong>assessment</strong> in association with early supported<br />

discharge improves functional outcomes and may reduce length of stay<br />

Notes For analysis this study has been divided in<strong>to</strong> the 2 interventions: CGA Ward plus Early<br />

Supported Discharge (ESD) and CGA Ward (no ESD)<br />

Risk of bias<br />

Bias Authors’ judgement Support <strong>for</strong> judgement<br />

Random sequence generation (selection<br />

bias)<br />

Low risk Random number sequence generation<br />

Allocation concealment (selection bias) Low risk Sealed opaque envelopes<br />

Blinding (per<strong>for</strong>mance bias and detection<br />

bias)<br />

All outcomes<br />

Incomplete outcome data (attrition bias)<br />

All outcomes<br />

Low risk Initial staff blinding. Blinded outcome <strong>assessment</strong><br />

Low risk Intention-<strong>to</strong>-treat analysis<br />

Selective reporting (reporting bias) Unclear risk No a priori documentation could be found<br />

<strong>to</strong> judge this item<br />

<strong>Comprehensive</strong> <strong>geriatric</strong> <strong>assessment</strong> <strong>for</strong> <strong>older</strong> <strong>adults</strong> <strong>admitted</strong> <strong>to</strong> hospital (Review)<br />

Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.<br />

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