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Emerging Business Models in the Pharmaceutical Industries ...

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Long Term Strategies - Biotech and Genomics<br />

Genomics and Proteomics: Higher Efficacy and<br />

Prediction Lead<strong>in</strong>g to Disease Management<br />

Eight of <strong>the</strong> 10 major causes of death <strong>in</strong> <strong>the</strong> US have<br />

genetic components. Genomics has evolved as a means of<br />

more effective personalised treatment.<br />

Advances <strong>in</strong> genomics and proteomics will allow patients to<br />

undergo predictive and preventive diagnostic tests for more<br />

than 750 known conditions. In genomic-based treatment,<br />

chronic and predictable diseases will be treated as normal,<br />

while acute and non-specific conditions will be considered<br />

more risky and profitable for <strong>the</strong> biotech companies.<br />

Pharma companies are focuss<strong>in</strong>g on streaml<strong>in</strong><strong>in</strong>g genomic<br />

mapp<strong>in</strong>g. There are 76 approved biotechnology medic<strong>in</strong>es<br />

today, with more than 360 <strong>in</strong> <strong>the</strong> pipel<strong>in</strong>e target<strong>in</strong>g over 200<br />

diseases.<br />

Nano Technology: Explor<strong>in</strong>g New Drug Delivery<br />

Mechanisms<br />

Pharma companies are consider<strong>in</strong>g <strong>the</strong> use of<br />

nanotechnology to augment <strong>the</strong> value of an orig<strong>in</strong>al<br />

<strong>in</strong>vention. Nano technologies help improve drug delivery,<br />

and extend <strong>the</strong> life of <strong>the</strong> drug. Accord<strong>in</strong>g to physicist and<br />

entrepreneur Michael Roukes, nano technologies facilitate<br />

medical care tailored explicitly and exactly to <strong>the</strong> <strong>in</strong>dividual.<br />

The emerg<strong>in</strong>g technology will provide a new approach for <strong>the</strong><br />

<strong>in</strong>vestigation of complex biological systems, measur<strong>in</strong>g drug<br />

effects, predict<strong>in</strong>g outcomes like silico, and improv<strong>in</strong>g <strong>the</strong><br />

R&D and manufactur<strong>in</strong>g processes.<br />

Nano technology is be<strong>in</strong>g fur<strong>the</strong>r developed <strong>in</strong> <strong>the</strong>se areas:<br />

• Microarrays/GeneChips<br />

• Microfluidics<br />

• Biosensors<br />

• Imag<strong>in</strong>g<br />

• High throughput DNA sequenc<strong>in</strong>g<br />

• Database m<strong>in</strong><strong>in</strong>g<br />

• Genome assembly<br />

• Target identification.<br />

<strong>Emerg<strong>in</strong>g</strong> technologies such as proteomics, biochips, signal<br />

transduction and toxicogenomics are chang<strong>in</strong>g <strong>the</strong> drug<br />

discovery landscape and creat<strong>in</strong>g new opportunities for<br />

pharmaceutical, biotechnology and o<strong>the</strong>r health-related<br />

companies.<br />

Strategic Analysis of <strong>the</strong> Pharma Market, Future Revenue <strong>Models</strong> and Key Players 26

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