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Emerging Business Models in the Pharmaceutical Industries ...

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Introduction<br />

Established <strong>in</strong> 1985, AstraZeneca plc is a<br />

research-based pharmaceutical company<br />

primarily engaged <strong>in</strong> provid<strong>in</strong>g effective<br />

medic<strong>in</strong>es to fight disease <strong>in</strong> <strong>the</strong><br />

cardiovascular, gastro<strong>in</strong>test<strong>in</strong>al,<br />

neuroscience, oncology, respiratory, and<br />

<strong>in</strong>flammation and <strong>in</strong>fection areas.<br />

The company has 31 manufactur<strong>in</strong>g sites <strong>in</strong><br />

20 countries, and employs over 60,000<br />

people worldwide. AstraZeneca has sales <strong>in</strong><br />

over 100 countries, with a strong presence <strong>in</strong><br />

European markets.<br />

With<strong>in</strong> Europe, France is <strong>the</strong> source of <strong>the</strong><br />

highest revenues for <strong>the</strong> company.<br />

Sales <strong>in</strong> 2003 totaled $18.8 billion, with an<br />

operat<strong>in</strong>g profit of $4.1 billion. The company<br />

spends over $14 million every work<strong>in</strong>g day on<br />

research and development.<br />

AstraZeneca<br />

Revenues<br />

The profit marg<strong>in</strong> fell due to decl<strong>in</strong>e <strong>in</strong> global sales of Losec/ Prilosec,<br />

Zestril and Nolvadex ($3 billion) follow<strong>in</strong>g <strong>the</strong>ir patent expiries. However it<br />

was partially offset with <strong>the</strong> performance of new and growth products <strong>in</strong><br />

<strong>the</strong>ir revitalised portfolio.<br />

The operat<strong>in</strong>g profits were not up to <strong>the</strong> mark as a result of planned<br />

<strong>in</strong>vestments <strong>in</strong> research and development, <strong>the</strong> cost of launch<strong>in</strong>g new<br />

products, and transformation of <strong>the</strong> product portfolio.<br />

20<br />

15<br />

10<br />

5<br />

0<br />

Astra-Zeneca's Five Year F<strong>in</strong>ancial Record<br />

(billion US$)<br />

25%<br />

1999 2000 2001 2002 2003<br />

Source: Company’s Annual Reports<br />

Strategic Analysis of <strong>the</strong> Pharma Market, Future Revenue <strong>Models</strong> and Key Players 73<br />

15%<br />

5%<br />

-5%<br />

Revenues<br />

Operat<strong>in</strong>g Profit<br />

Profit Marg<strong>in</strong>

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