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Redesigning Animal Agriculture

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228 Index<br />

RNA interference (RNAi) (continued)<br />

role in viral-directed immunity 127<br />

what is it? 125<br />

see also DNA delivered RNA interference<br />

(ddRNAi)<br />

RNA polymerase III promoters 125, 131, 133, 136<br />

categories 133–134<br />

RNA silencing pathways 125, 127<br />

RNAse III enzymes (Dicer) 127, 128<br />

rodents, germ cell transplantation 82, 84<br />

Rollin, Tom 35, 40, 41<br />

ruminants, success as a group 51<br />

rural communities 22–24<br />

ageing demographic 19<br />

decline in levels of social capital 24<br />

decline in young professionals 22<br />

‘downshifters’ moving into 22<br />

drought effects 21, 23–24<br />

educational access 23<br />

employment decline 21, 23<br />

environmental degradation 25<br />

gender drift 22<br />

health levels among 22–23<br />

and healthy agricultural sector 19<br />

impact of restructuring and neoliberal policies<br />

on 19, 20, 24–25<br />

investment in 25–26<br />

environmental capital 26<br />

human capital 26<br />

international capital 26<br />

lifestyle factors affecting 19, 21<br />

little to attract young people 19, 22<br />

loss of young people 22, 27<br />

maintaining vibrant 18–27, 212<br />

male suicide 23<br />

multifunctionality 24–26<br />

population decline 22<br />

pressures on 19<br />

removal of services from 24<br />

retirees moving to 22<br />

significance for farm families 21<br />

stresses on 22–23<br />

‘tree-changers’ moving into 22<br />

why are they needed? 24–26<br />

see also farm families in Australia<br />

rural farming communities, need to establish<br />

partnerships with urban/non-farming<br />

communities 213<br />

rural women<br />

domestic violence towards 23<br />

employment of 21<br />

Salner, M 9, 10, 13–14<br />

scientists<br />

as participants in systems of nature 13<br />

as ‘public decision makers’ 12<br />

scrapie 55<br />

Second Order Systemics 6, 9<br />

sediment input into Great Barrier Reef<br />

Lagoon 174<br />

selective breeding 47<br />

seminiferous tubule colonization by transplanted<br />

germ cells 84<br />

need for endogenous germ cell<br />

depletion 84–85<br />

sequential gene targeting 100<br />

Sertoli cells<br />

germ cell recognition 82<br />

pre-pubertal animals 84<br />

severe acute respiratory syndrome (SARS) 134<br />

sewage treatment works, P and N removal,<br />

EU 188<br />

sheep industry 21<br />

sheep production, diffuse nutrient export, UK<br />

waters 194, 195, 197<br />

short hairpin RNA (shRNA) 131<br />

effector molecule design 133<br />

structure 132<br />

short hairpin RNA (shRNA) expression 131<br />

inducible promoter systems 131<br />

viral-based systems 131–132<br />

shRNA-mediated ddRNAi 132<br />

for avian influenza resistant poultry 136<br />

Singer, Peter 34, 35, 37<br />

Sire Model 67<br />

small interfering RNA (siRNA) 126<br />

in RNAi cellular mechanism 128, 129<br />

role in gene expression 127<br />

synthetic 129–131<br />

small interfering RNA (siRNA) expression,<br />

DNA-delivered 131–132<br />

SNP (Single Nucleotide Polymorphism)<br />

markers 72, 75<br />

bovine genome 51, 52, 53–54, 56<br />

number required dependent on linkage<br />

disequilibrium 54<br />

social aspects of sustainable livestock<br />

development 206–207<br />

social capital, decline in rural communities 24<br />

social sustainability of agriculture 18–19<br />

social systems 5<br />

societal values, changing towards agriculture of<br />

livestock and the environment 212–214<br />

somatic cell nuclear transfer 94, 95<br />

in animal species 95<br />

animal welfare concerns 110<br />

disease model applications 104<br />

donor cells 95–96<br />

efficiency 96<br />

in farm animals 99<br />

impact of stage of donor cell cycle on<br />

efficiency 96<br />

mortality rates in cattle 96

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