Duke University 2008-2009 - Office of the Registrar - Duke University

gonad, lung, heart, head and neural tube, and appendage and heart regeneration. Specific
interests in cellular, organ, and systemic physiology include neuro-muscular junctions, the
cellular basis of addiction and innate immunity, as well as heart, lung, gut, muscle, and
reproductive organ function. The department has excellent facilities, including a state-ofthe-art
confocal microscopy suite with time-lapse live cell video imaging, phosphor
autoradiography, four-color fluorescent scanning/multiplexing, zebrafish facility, mouse
genetics, and micromanipulation..
The Department of Cell Biology participates in several university-wide
interdisciplinary training programs, including genetics, cell and molecular biology,
developmental biology, neurobiology, pharmacology, cancer biology, biomedical
engineering, and toxicology. Admission to graduate training in cell biology is through one
of these interdisciplinary programs. For more information, contact the director of graduate
studies.
200. Cell and Tissue Biology. This is the introductory medical school and graduate course
in microscopic anatomy. Students participate in lectures and laboratories on the structure
and function of cells and tissues of the body. The courses provides practical experience in
the use of the light microscope analyzing an extensive slide collection of mammalian tissues.
3 credits. McIntosh and staff. 3 units.
201. Microscopic Anatomy. Histology of all major organs of the body. Structure and cell
biology at both the level of the light and electron microscope. 3 credits. McIntosh and staff.
3 units.
202. Medical Physiology. Medical and graduate level course on organ and cell physiology.
Human and medical aspects are stressed. 4 credits. Anderson and staff. 4 units.
203. Introduction to Physiology. Modern organ physiology; cellular physiology, organ
system physiology including cardiovascular, respiratory, renal gastrointestinal, endocrine,
reproductive, muscle and nervous. Mini course. Prerequisite: elementary biology.
Instructors: Jakoi and Vigna. 3 units.
206. Physiology and Medicine of Extreme Environments. Advanced topics in the
physiology and medicine of ambient pressure, immersion, gravity, temperature, and gas
composition. Environments include diving and hyperbaric medicine; hot/cold terrestrial and
water operations; microgravity and high-g acceleration; high altitude. Examines basic
mechanisms and medical management of associated diseases including decompression
sickness; altitude sickness; hypothermia and hyperthermia; hypoxia; carbon monoxide
poisoning; oxygen toxicity. Laboratory optional. Prerequisites: human anatomy and
physiology; diving techniques, equipment, and procedures; diving physiology, dysbaric
diseases, and treatments. Instructor: Staff. Variable credit.
208. Stem Cell Biology Minicourse. 2 units. C-L: see Molecular Cancer Biology 208
210. Research Independent Study. Individual Research in a field of special interest under
the supervision of a faculty member, the central goal of which is a substantive paper or
written report containing significant analysis and interpretation of a previously approved
topic. Consent of instructor required. Instructor: Staff. Variable credit. C-L: Marine
Sciences
212. Topics in Reproductive Biology. An in-depth, integrative study of male and female
reproduction, including (i) hypothalamic, pituitary, and gonadal control mechanisms, (ii)
gamete structure and development, (iii) fertilization, and (iv) pregnancy and parturition.
Guest lectures will emphasize the interface between basic, veterinary, and medical sciences.
Prerequisite: Cell Biology 269 or equivalent. Instructor: N. Anderson, Saling, Schomberg,
or Tyrey. 3 units.
241. Cell Biological Processes. This course is a graduate level introduction to the molecular
mechanisms that underlie cellular processes and the experimental techniques used in cell
biological research. The lectures will address the processes that cells use to organize
themselves into tissues and organs, communicate through second messengers, generate
Courses of Instruction 94