Donepezil, rivastigmine, galantamine and memantine for ...

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Feedback The HTA Programme and the authors would like to know your views about this report. The Correspondence Page on the HTA website (http://www.ncchta.org) is a convenient way to publish your comments. If you prefer, you can send your comments to the address below, telling us whether you would like us to transfer them to the website. We look forward to hearing from you. The National Coordinating Centre for Health Technology Assessment, Mailpoint 728, Boldrewood, University of Southampton, Southampton, SO16 7PX, UK. Fax: +44 (0) 23 8059 5639 Email: hta@soton.ac.uk http://www.ncchta.org ISSN 1366-5278
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Health Technology Assessment 2006;
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The clinical and cost-effectiveness
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Objectives: To provide an update re
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List of abbreviations .............
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AChEI acetylcholinesterase inhibito
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Epidemiology and background Alzheim
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Galantamine Five published economic
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Description of underlying health pr
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TABLE 1 Estimated prevalence of AD
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as one component of their care. A n
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The a priori methods used for syste
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Data synthesis Data were synthesise
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14 Clinical effectiveness TABLE 3 C
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16 Clinical effectiveness TABLE 3 C
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18 Clinical effectiveness particula
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20 Clinical effectiveness Compariso
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22 Clinical effectiveness TABLE 6 M
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24 Clinical effectiveness donepezil
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32 Clinical effectiveness DAD The D
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34 Clinical effectiveness clinical
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36 Clinical effectiveness TABLE 10
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40 Clinical effectiveness statistic
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46 Clinical effectiveness Summary:
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48 Clinical effectiveness differenc
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52 Clinical effectiveness This appe
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62 Clinical effectiveness placebo [
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66 Clinical effectiveness (24 mg/da
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70 Clinical effectiveness ● One R
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72 Clinical effectiveness by the pa
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78 Clinical effectiveness donepezil
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80 Evidence from systematic reviews
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82 Economic analysis TABLE 48 Chara
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84 TABLE 49 Economic analysis Outli
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86 Economic analysis The UK study r
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88 Economic analysis The AD2000 stu
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90 Economic analysis term). Where w
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92 Economic analysis published econ
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94 Economic analysis Fenn and Gray
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96 Economic analysis one another. W
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98 Economic analysis outcomes: (1)
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100 Economic analysis respond to ga
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102 Economic analysis donepezil, ri
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104 Economic analysis of this study
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106 Economic analysis independent,
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108 Economic analysis classificatio
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110 Economic analysis survey studie
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112 Economic analysis vascular deme
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114 Economic analysis Livingston an
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116 Economic analysis sensitive to
Page 132 and 133: 118 Economic analysis Neumann and c
Page 134 and 135: 120 Economic analysis The model str
Page 136 and 137: 122 Economic analysis CEA, given th
Page 138 and 139: 124 Economic analysis TABLE 70 Key
Page 140 and 141: 126 Economic analysis TABLE 73 Prof
Page 142 and 143: 128 Economic analysis Probability o
Page 144 and 145: 130 Economic analysis Results are s
Page 146 and 147: 132 Economic analysis 4. The model
Page 148 and 149: 134 Economic analysis perspective e
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Page 153: Ongoing research, with relevance to
Page 157: The increasing numbers of the very
Page 160 and 161: 146 Discussion and conclusions dose
Page 162 and 163: 148 Discussion and conclusions effo
Page 164 and 165: 150 Discussion and conclusions Stre
Page 167 and 168: 1. Clegg A, Bryant J, Nicholson T,
Page 169 and 170: placebo-controlled study of donepez
Page 171 and 172: 94. Brooks E, Deal L. The effect of
Page 173 and 174: of memantine in patients with moder
Page 175: This version of HTA monograph volum
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