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Strabismus - Fundamentals of Clinical Ophthalmology.pdf

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CHILDHOOD ONSET OF STRABISMUS<br />

(a)<br />

(b)<br />

Figure 4.13 Alternating divergent strabismus. Constant alternating divergent strabismus in a 3 year old<br />

child. Note alternation <strong>of</strong> fixation. Most children have a transient exotropia in the first weeks <strong>of</strong> life.<br />

It is important to exclude any neurological deficits. This child had no binocular vision in the absence <strong>of</strong> a<br />

neurological defect<br />

Though the vast majority <strong>of</strong> Intermittent<br />

exotropias are probably the result <strong>of</strong> a static<br />

underlying cause, it is important to keep in mind<br />

any clue alerting the clinician to a possible loss<br />

<strong>of</strong> visual field, frustrating sufficient overlapping<br />

to meet the needs <strong>of</strong> normal binocular vision.<br />

Congenital exotropia that persists is a different<br />

matter. A large angle up to 50 prism dioptres may<br />

be present with a constant exotropia. Because <strong>of</strong><br />

the frequency <strong>of</strong> associated neurological disease,<br />

referral to a paediatric neurologist is advised.<br />

Differential diagnosis includes developmental<br />

defects in the deviating eye and congenital cranial<br />

nerve palsies. Local causes <strong>of</strong> defective vision<br />

need to be excluded. A careful developmental<br />

history will frequently reveal abnormal milestones<br />

if there is underlying neurological disease. In the<br />

context <strong>of</strong> neurological disease, for example<br />

neur<strong>of</strong>ibromatosis, the exotropia may signal the<br />

presence <strong>of</strong> a progressive disease (Figure 4.12),<br />

frequently affecting the sensory arc <strong>of</strong> the visual<br />

path. Early surgery by the age <strong>of</strong> 2 years will<br />

achieve a more stable alignment for distance, but<br />

is <strong>of</strong>ten at the cost <strong>of</strong> a mon<strong>of</strong>ixation syndrome.<br />

Surgery by the age <strong>of</strong> 4 or 5 years appears to be<br />

associated with a higher risk <strong>of</strong> intermittent<br />

divergence persisting. Surgery for patients under<br />

the age <strong>of</strong> 4 years gives complete cure in about<br />

50% <strong>of</strong> cases. Lateral incomitance may exist in<br />

about 5% <strong>of</strong> exotropes, 10 and needs to be<br />

identified as a failure to recognise it may result in<br />

surgical overcorrections. It is also important to<br />

note that a child with an alternating divergent<br />

fixation present at distance and near may have no<br />

underlying neurological defect (Figure 4.13).<br />

Management<br />

The options in management include minus<br />

lenses in glasses if the patient is myopic.<br />

Deliberate overcorrection with concave lenses<br />

aims to induce accommodation to assist control<br />

<strong>of</strong> the deviation, and may have a limited place<br />

in management. Surgical correction involves<br />

bilateral lateral rectus recessions up to 11 mm<br />

from the limbus. Medial rectus resection in<br />

patients with a convergence insufficiency type <strong>of</strong><br />

exophoria also has a limited value. Complications<br />

<strong>of</strong> surgery include underactions in over 25% <strong>of</strong><br />

cases. Surgical alignment occurs in as many as<br />

80% with good cosmetic prospects, but only 50%<br />

have good binocular vision after surgery.<br />

35

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