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Annual report National Notifiable Diseases Surveillance System, 2004<br />

Ross River virus infection<br />

Case defi nition – Ross River virus infection<br />

Only confirmed cases are reported.<br />

Confirmed case: Requires isolation <strong>of</strong> Ross<br />

River virus, OR detection <strong>of</strong> Ross River virus by<br />

nucleic acid testing, OR IgG seroconversion or a<br />

significant increase in antibody level or a fourfold<br />

or greater rise in titre to Ross River virus,<br />

OR detection <strong>of</strong> Ross River virus-specific IgM.<br />

There were 4,000 notifi cations <strong>of</strong> Ross River virus<br />

(RRV) infection reported to NNDSS in 2004, which<br />

accounts for two-thirds (67%) <strong>of</strong> the total mosquitoborne<br />

disease notifi cations received in 2004.<br />

The highest contributors to RRV notifications in 2004<br />

were Queensl<strong>and</strong> (45%, n=1,795), Western Australia<br />

(27%, n=1,099), <strong>and</strong> New South Wales (18%, n=700).<br />

The highest rates <strong>of</strong> infection were reported by the<br />

Northern Territory (117.6 cases per 100,000 population),<br />

Western Australia (55.4 cases per 100,000), <strong>and</strong><br />

Queensl<strong>and</strong> (46.2 cases per 100,000 population).<br />

The 2004 national RRV notification rate (19.9 cases<br />

per 100,000) was the third highest RRV notification<br />

rate reported to NNDSS since 1999.<br />

Map 8 shows that the highest rate <strong>of</strong> RRV infection in<br />

2004, was in the Kimberley region area <strong>of</strong> Western<br />

Australia (202.8 cases per 100,000 population).<br />

RRV infection notifi cations in the Northern Territory<br />

peaked in January 2004 at 606.3 cases per 100,000<br />

population (Figure 51). This was the highest rate<br />

since 1999, closely resembling the RRV peak notifi<br />

cation rate <strong>and</strong> pr<strong>of</strong>i le in the Northern Territory in<br />

Figure 51. Notification rates for Ross River<br />

virus infection, select jurisdictions, 1999 to 2004,<br />

by month <strong>and</strong> season <strong>of</strong> onset<br />

700<br />

January 2001. Queensl<strong>and</strong> reported the peak notifi<br />

cation rate for RRV in March 2004 at 216.7 cases<br />

per 100,000 population, <strong>and</strong> this was a 24 per cent<br />

reduction from the peak notifi cation rate for April<br />

2003 (286.3 cases per 100,000 population).<br />

In Western Australia, a state-wide outbreak <strong>of</strong> RRV<br />

peaked in January 2004 at 263.9 cases per 100,000<br />

population which was the largest recorded outbreak<br />

<strong>of</strong> RRV in Western Australia 21,22 despite early warning<br />

through media <strong>and</strong> publicity channels. The predisposing<br />

environmental, entomological <strong>and</strong> virological<br />

aspects <strong>of</strong> the outbreak have been described elsewhere.<br />

22,23<br />

The age <strong>and</strong> sex distribution <strong>of</strong> RRV notifi cations are<br />

shown in Figure 52. The notification rates were highest<br />

in the 40–44 age group (38.9 cases per 100,000<br />

population) <strong>and</strong> the female to male ratio was 1:0.9.<br />

Figure 52. Notification rates for Ross River<br />

virus infection, Australia, 2004, by age group<br />

<strong>and</strong> sex<br />

Rate per 100,000 population<br />

45<br />

40<br />

35<br />

30<br />

25<br />

20<br />

15<br />

10<br />

5<br />

0<br />

0-4<br />

5-9<br />

10-14<br />

15-19<br />

20-24<br />

25-29<br />

30-34<br />

35-39<br />

40-44<br />

45-49<br />

50-54<br />

55-59<br />

60-64<br />

65-69<br />

70-74<br />

75-79<br />

80-84<br />

85+<br />

Flaviviruses<br />

Age group (years)<br />

Male<br />

Female<br />

Flaviviruses are single-str<strong>and</strong>ed RNA viruses, some<br />

<strong>of</strong> which are associated with epidemic encephalitis<br />

in various regions <strong>of</strong> the world. In Australia, the<br />

flaviviruses <strong>of</strong> public health importance are Murray<br />

Valley encephalitis virus (MVEV), Kunjin virus<br />

(KUNV), Japanese encephalitis <strong>and</strong> dengue viruses.<br />

Rate per 100,000 population<br />

600<br />

500<br />

400<br />

300<br />

200<br />

100<br />

0<br />

Jan<br />

1999<br />

Jul<br />

Jan<br />

2000<br />

Jul<br />

Jan<br />

2001<br />

Jul<br />

Northern Territory<br />

Queensl<strong>and</strong><br />

Western Australia<br />

Jan<br />

2002<br />

Jul<br />

Jan<br />

2003<br />

Month <strong>and</strong> year <strong>of</strong> onset<br />

Jul<br />

Jan<br />

2004<br />

Jul<br />

The Sentinel Chicken Programme is a surveillance<br />

network involving New South Wales, the Northern<br />

Territory, Victoria <strong>and</strong> Western Australia, <strong>and</strong> is<br />

designed to provide early warning <strong>of</strong> increased<br />

fl avivirus activity. 24 Antibodies to MVEV <strong>and</strong> KUNV are<br />

detected in sentinel fl ocks located in four Australian<br />

states. Sentinel chicken surveillance reports from<br />

previous seasons have been published, 25–27 <strong>and</strong><br />

the latest report was published in CDI in 2005 as<br />

part <strong>of</strong> the National Arbovirus <strong>and</strong> Malaria Advisory<br />

Committee annual report, 2004–05. 28<br />

56 CDI Vol 30 No 1 2006

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