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National Notifiable Diseases Surveillance System, 2004<br />

Annual report<br />

Following the deliberate release <strong>of</strong> anthrax spores<br />

in the United States <strong>of</strong> America in 2001, anthrax<br />

became a nationally notifi able disease in Australia.<br />

In 2004, no cases <strong>of</strong> anthrax were notifi ed. The<br />

last reported human cases <strong>of</strong> anthrax in Australia<br />

(both cutaneous anthrax) occurred in July 1998 <strong>and</strong><br />

February 1997.<br />

Anthrax is a notifi able animal disease subject to<br />

compulsory government control strategies including:<br />

vaccination <strong>of</strong> susceptible livestock located on sites<br />

with a known history <strong>of</strong> anthrax; epidemiological<br />

investigation <strong>of</strong> outbreaks; quarantine <strong>and</strong> decontamination<br />

<strong>of</strong> affected premises; <strong>and</strong> safe disposal <strong>of</strong><br />

carcases. Certain rural areas in central New South<br />

Wales <strong>and</strong> northern <strong>and</strong> north-eastern Victoria are<br />

associated with recurring cases <strong>of</strong> anthrax in cattle<br />

<strong>and</strong> sheep. In these endemic areas, anthrax has a<br />

low <strong>and</strong> decreasing prevalence. Cases only occur<br />

sporadically, mostly in partially vaccinated animals.<br />

In 2004, 15 outbreaks <strong>of</strong> anthrax were reported in<br />

livestock (13 from New South Wales <strong>and</strong> 2 from<br />

Victoria). Only one <strong>of</strong> these outbreaks was from outside<br />

the known anthrax endemic areas, on a farm<br />

that was part <strong>of</strong> an old stock route leading to the<br />

endemic zone in New South Wales. In all instances<br />

the usual protocols <strong>of</strong> quarantine, disinfection <strong>of</strong><br />

contaminated ground, carcass incineration, <strong>and</strong><br />

vaccination <strong>of</strong> the herd <strong>and</strong> neighbouring herds<br />

were implemented. All animal movements from<br />

affected properties were traced <strong>and</strong> there was no<br />

risk <strong>of</strong> further spread <strong>of</strong> disease.<br />

Australian bat lyssaviral <strong>and</strong> lyssaviral<br />

(unspecified) infections<br />

Case defi nition – Lyssavirus (unspecifi ed)<br />

Only confirmed cases are reported AND only<br />

where there is insuffi cient evidence to meet a<br />

case defi nition for Australian bat lyssavirus or<br />

rabies.<br />

Confirmed case: Requires positive fl uorescent<br />

antibody test result for lyssaviral antigen on<br />

fresh brain smears, OR specifi c immunostaining<br />

for lyssaviral antigen on formalin fi xed<br />

paraffi n sections <strong>of</strong> central nervous system<br />

tissue, OR presence <strong>of</strong> antibody to serotype 1<br />

lyssavirus in the cerebrospinal fl uid, OR detection<br />

<strong>of</strong> lyssavirus-specifi c RNA (other than to<br />

Australian bat lyssavirus or rabies).<br />

Case defi nition – Australian bat lyssavirus<br />

Only confirmed cases are reported.<br />

Confirmed case: Requires isolation <strong>of</strong><br />

Australian bat lyssavirus confi rmed by<br />

sequence analysis, OR detection <strong>of</strong> Australian<br />

bat lyssavirus by nucleic acid testing.<br />

No new cases <strong>of</strong> either Australian bat lyssaviral<br />

or lyssaviral (unspecifi ed) infections were notifi<br />

ed during 2004. Two cases <strong>of</strong> human infection<br />

with Australian bat lyssavirus, in 1996 <strong>and</strong> 1998,<br />

occurred following close contact between bat-h<strong>and</strong>lers<br />

<strong>and</strong> infected bats. Both resulted in the death <strong>of</strong><br />

the infected person.<br />

There are two strains <strong>of</strong> Australian bat lyssavirus<br />

known: one circulates in frugivorous bats, suborder<br />

Megachiroptera, <strong>and</strong> the other circulates in<br />

the smaller, mainly insectivorous bats, sub-order<br />

Microchiroptera. Each strain has been associated<br />

with one human fatality. Surveillance indicates<br />

infected bats are widespread at a low frequency on<br />

the Australian mainl<strong>and</strong>. 37 Research into the genetic<br />

sequences <strong>of</strong> lyssaviruses isolated from different<br />

groups <strong>of</strong> bats using molecular methods suggests<br />

that the virus has been associated with bats in<br />

Australia for more than 1,500 years. 38 That is, the<br />

virus was well established before European colonisation,<br />

<strong>and</strong> its recent ‘emergence’ is in all likelihood<br />

due to changes in human behaviour <strong>and</strong> encroachment<br />

on bat habitats.<br />

Brucellosis<br />

Case defi nition – Brucellosis<br />

Only confirmed cases are reported.<br />

Confirmed case: Requires isolation <strong>of</strong><br />

Brucella species, OR IgG seroconversion<br />

or a signifi cant increase in antibody level or<br />

a fourfold or greater rise in titre in Brucella<br />

agglutination titres or complement fi xation titres<br />

between acute <strong>and</strong> convalescent phase serum<br />

samples. (Where possible both tests should be<br />

conducted at the same laboratory), OR a single<br />

high Brucella agglutination titre.<br />

AND Acute encephalomyelitis with or without<br />

altered sensorium or focal neurological signs.<br />

CDI Vol 30 No 1 2006 63

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