6100CR Refrigerated Sampler - Isco

6100CR Refrigerated Sampler
Appendix B Material Safety Data Sheets
H&S: 1,2-PROPANEDIOL 57-55-6 Page 3 of 7
LD50 ipr rat 6660 mg/kg
LDLo ivn ckn 27 gm/kg
LD50 ivn dog 26 gm/kg
LD50 ivn mus 6630 mg/kg
LD50 ivn rat 6423 mg/kg
LDLo ivn rbt 4200 mg/kg
TDLo orl chd 79 gm/kg/56W-I
LD50 orl dog 22 gm/kg
LD50 orl gpg 19 gm/kg
LD50 orl mus 24 gm/kg
LD50 orl rat 20 gm/kg
LDLo orl rbt 14300 mg/kg
LDLo scu gpg 15500 mg/kg
LD50 scu mus 17370 mg/kg
LD50 scu rat 22500 mg/kg
LD50 skn rbt 20800 mg/kg
*AQTX/TLM96: over 1000 ppm
*SAX TOXICITY EVALUATION:
THR: A skin and eye irritant. It affects the central nervous system in
humans. LOW via oral, intraperitoneal, subcutaneous, intramuscular and
skin routes. It is a substance which migrates to food from packaging
materials.
*CARCINOGENICITY: Not available
*MUTATION DATA:
test lowest dose | test lowest dose
----------- ----------------- | ----------- -----------------
cyt-ham:fbr 32 gm/L | cyt-mus-scu 8000 mg/kg
dni-mus-scu 8000 mg/kg |
*TERATOGENICITY:
Reproductive Effects Data:
TDLo: ipr-mus 100 mg/kg (11D preg)
TDLo: ipr-mus 100 mg/kg (15D preg)
*STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
*OTHER TOXICITY DATA:
Skin and Eye Irritation Data:
skn-hmn 500 mg/7D MLD
skn-hmn 104 mg/3D-I MOD
skn-man 10%/2D
eye-rbt 100 mg MLD
eye-rbt 500 mg/24H MLD
Review: Toxicology Review
Status: EPA Genetox Program 1986, Negative: SHE-clonal assay
EPA TSCA Chemical Inventory, 1986
EPA TSCA Section 8(e) Status Report 8EHQ-0178-0041
EPA TSCA Test Submission (TSCATS) Data Base, December 1986
Meets criteria for proposed OSHA Medical Records Rule
-OTHER DATA (Regulatory)
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