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NEUROPHYSIOLOGY<br />
Olfactory System: Pathway<br />
Efferent fibers<br />
Afferent fibers<br />
Granule cell (excited by<br />
and inhibiting to mitral<br />
and tufted cells)<br />
Mitral cell<br />
Recurrent process<br />
Tufted cell<br />
Periglomerular<br />
cell<br />
Glomerulus<br />
Olfactory<br />
nerve fibers<br />
Fibers from contralateral olfactory bulb<br />
Fibers to contralateral olfactory bulb<br />
Anterior commissure<br />
Medial olfactory stria<br />
Olfactory trigone and<br />
olfactory tubercle<br />
Anterior perforated<br />
substance<br />
Lateral olfactory<br />
stria<br />
Lateral olfactory<br />
tract nucleus<br />
Piriform lobe<br />
Uncus<br />
Amygdala<br />
(in phantom)<br />
Entorhinal area<br />
Olfactory epithelium<br />
Olfactory nerves<br />
Olfactory bulb<br />
Olfactory tract<br />
Anterior olfactory nucleus<br />
Cribriform plate of ethmoid bone<br />
©<br />
FIGURE 2.41<br />
OLFACTORY PATHWAY •<br />
Olfactory stimuli are detected by the nerve fibers of the olfactory<br />
epithelium and conveyed to the olfactory bulb (detailed local circuitry<br />
shown in upper left panel). Integrated signals pass along the<br />
olfactory tract and centrally diverge to pass to the anterior commissure<br />
(some efferent projections course to the contralateral olfactory<br />
bulb, blue lines) or terminate in the ipsilateral olfactory trigone<br />
(olfactory tubercle). Axons then project to the primary olfactory<br />
cortex (piriform cortex), entorhinal cortex, and amygdala.<br />
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