30.08.2014 Views

biologia - Studia

biologia - Studia

biologia - Studia

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

R. TOROK OANCE, V. NICULESCU, M.N. FILIMON<br />

noticed four different situations. The most frequent was the situation of vertebral<br />

osteoporosis associated with hip osteopenia. In all cases<br />

there was affected the vertebral column.<br />

There are multiple causes for the discordance in diagnosis. They can be of<br />

a physiological nature, connected to the natural adaptive reaction of the skeleton to<br />

internal and external factors, of a physiopathological nature, as a consequence of an<br />

anatomical affection and connected to the presence and composition of the surrounding<br />

tissues, of technical nature, concerning the equipment used for determination or the<br />

faulty determination. Moayyeri et al., (2005) have researched this discordance in<br />

diagnosis in osteoporosis. Most of the patients included in their research (58.3%)<br />

had the same T-score categories both at the vertebral column and at the hip bone, a<br />

minor discordance in diagnosis was encountered in 38.9% of the cases, while a<br />

major discordance was found in only 2.7% of the cases.<br />

Our results are slightly different. The cases with a major discordance in<br />

diagnosis are the rarest situation as well (9.72%). This is followed by the situation<br />

in which osteoporosis is diagnosed for both regions, the most frequent being the minor<br />

discordance in diagnosis (61.38%). According to Masud and Francis (2000), the<br />

discordance is more frequent in the first years of postmenopause than in women<br />

over 60 years old.<br />

Conclusions<br />

In the set of patients we analyzed, the decrease of the bone mineral density<br />

starts after the age of 40, both at the vertebral column, and at the hip bone. This<br />

decrease of the bone mineral density becomes more significant after the age of 70,<br />

in both determination regions.<br />

There is an inverted connection, tight and very significant (p=0.0038), between<br />

the bone mineral density determined at the vertebral column and age. Likewise, there is<br />

an inverted connection, tight and very significant, between the bone mineral density<br />

determined at the hip bone and age (p=0.0017), the connection being even tighter than<br />

in the previous case (p=0.0017).<br />

We also noticed the existence of a direct and not very tight connection<br />

between the bone mineral density determined at the vertebral column and, respectively,<br />

at the hip bone; the R correlation quotient’s value is 0.4539 (R 2 = 0.2044, p=0.6786).<br />

There is also an obvious decrease tendency, with increasing age, of the T-<br />

score values, both at the vertebral column, and at the hip bone. On the other hand,<br />

the Z-score, which also takes into account the patient’s age, shows an increase<br />

tendency both at the vertebral column, and at the hip bone.<br />

In the set of patients we analyzed, we noticed, according to the T-score, that<br />

the axial skeleton is preponderantly affected. The most frequent situations are those of<br />

minor discordance of diagnosis between the two regions under investigation, followed<br />

by the cases of the unitary diagnosis. The least frequent was the major discordance of<br />

100

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!