biologia - Studia

STUDIA UNIVERSITATIS BABEŞ – BOLYAI, BIOLOGIA, LV, 1, 2010, p. 91-101
MODIFICATION OF THE BONE MINERAL DENSITY, T-SCORE
AND Z-SCORE VALUES ACCORDING TO AGE AND ANATOMIC
REGION IN OSTEOPOROSIS CASES
RODICA TÖRÖK-OANCE 1 , VIRGILIU NICULESCU 2 and
MARIOARA NICOLETA FILIMON 3
SUMMARY. The bone resistance largely depends on the bone mineral
density. Osteoporosis is a disease in which the bone resistance is affected, and
establishing a diagnostic of certainty can be achieved by determining the bone
mineral density. The present paper is based on the analysis of the results of
the osteodensitometric investigation conducted on 361 patients who had been
diagnosed with primary or secondary osteoporosis. The investigation took
into account the hip bone and the vertebral column, and the following
parameters have been analyzed: bone mineral content, bone mineral density,
T-score and Z-score. We analyzed the evolution of the bone mineral density
with increasing age, the existence of a connection between the bone mineral
density determined at the vertebral column and at the hip, the connection
between the T- and Z-score and age at the population we took into account, as
well as the existence and the type of discordance in diagnosis for the two
points of determination.
We found out that there is a decrease in the bone mineral density
above the age of 40; concerning the T-score, there is an obvious decrease
tendency with ageing, both at the vertebral column and at the hip, while in
the case of the Z-score, the tendency is that of increasing with age. The
most frequent discordance in diagnosis found in the population we
analyzed is the minor one. The axial skeleton is preponderantly affected.
Keywords: age, bone mineral density, osteoporosis, T-score, Z-score
Introduction
The bone mineral density represents the decisive element of bone resistance,
explaining for the most part its variability. The bone density expresses the bone quantity
1 West University of Timişoara, Faculty of Chemistry, Biology and Geography, Department of
Biology, str. Pestalozzi, 16, Timisoara, Romania. E-mail: rodica.torok@cbg.uvt.ro
2 University of Medicine and Pharmacy „Victor Babeş” Timişoara, Department of Anatomy;
3 West University of Timişoara, Faculty of Chemistry, Biology and Geography, Department of Biology.