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Siratro Extract BG - Cosmesi.it

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NIKKO CHEMICALS CO., LTD.<br />

1-4-8 NIHONBASHI-BAKUROCHO, CHUOKU, TOKYO, 103-0002, JAPAN Email: inter@nikkol.co.jp www.nikkol.co.jp<br />

Natural Emulsifier for Sens<strong>it</strong>ive Skin Care<br />

Lecinol S-10<br />

Anti-inflammatory<br />

inflammatory<br />

Hydrogenated lec<strong>it</strong>hin derived from soy bean. Contains 25-30% of Phosphatidyl Choline. Natural<br />

emulsifier w<strong>it</strong>h anti-inflammatory properties. Effectively reduces irr<strong>it</strong>ation. Decreases irr<strong>it</strong>ation potential<br />

of other surfactants. Enhances anti-inflammatory properties of oil-soluble actives (e.g. Stearyl<br />

Glycyrrhetinate). Emulsions made w<strong>it</strong>h Lecinol S-10 enhance percutaneous of active ingredients.<br />

Prevention of corneocytes’ damage<br />

caused by Sodium Lauryl Sulfate (SLS).<br />

Closed patch (SLS: 5%); after 72 hours.<br />

Microscope photograph of<br />

corneocytes.<br />

Lecinol S-10 protects stratum corneum<br />

from damage by strong detergents.<br />

Non-treated cells<br />

Cells treated w<strong>it</strong>h<br />

1% Lecinol S-10<br />

Anti-stinging effect (in vivo)<br />

Weak Strong<br />

Average stinging score<br />

3<br />

2<br />

1<br />

Before<br />

After 1 week<br />

application of<br />

Lecinol S-10<br />

(1.0%)<br />

Water<br />

NEW<br />

DATA<br />

0.1%<br />

methylparaben<br />

solution<br />

Anti-inflammatory effect: inhib<strong>it</strong>ion of<br />

Prostaglandin E2 (in v<strong>it</strong>ro)<br />

Application of Lecinol S-10 at 1.0% significantly<br />

reduced average stinging score against<br />

methylparaben solution (after 1 week; n=13).<br />

Control: Water 0.1% MP sol.<br />

Number of subjects who showed<br />

reduction of stinging score after 1 week<br />

application of Lecinol S-10 (1.0%)<br />

1 (8%) 7 (54%)<br />

2009-12

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