Siratro Extract BG - Cosmesi.it
Siratro Extract BG - Cosmesi.it
Siratro Extract BG - Cosmesi.it
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
NIKKO CHEMICALS CO., LTD.<br />
1-4-8 NIHONBASHI-BAKUROCHO, CHUOKU, TOKYO, 103-0002, JAPAN Email: inter@nikkol.co.jp www.nikkol.co.jp<br />
Anti-age / Anti-stress / AQP3<br />
Tocoretinate-10<br />
Caprylic/capric triglyceride solution containing 10% of an ester of retinoic acid and natural v<strong>it</strong>amin E.<br />
Effectively reduces skin wrinkles at 1% concentration (clinically tested). Promotes collagen synthesis.<br />
Scavenges active oxygen species. Does not release retinoic acid due to the resistance to<br />
breakdown by esterase. Low skin irr<strong>it</strong>ation potential.<br />
Suppression of DNA damage induced by UVB (Comet Assay test)<br />
Tail length (mm)<br />
120<br />
100<br />
80<br />
60<br />
40<br />
** ** **<br />
Control<br />
67.2 mM<br />
UVB 10mJ/cm 2<br />
92.4 mM<br />
DNA damage was<br />
evaluated by the<br />
comet assay. HaCaT<br />
keratinocytes which<br />
were treated w<strong>it</strong>h<br />
Tocoretinate for 24 h,<br />
were exposed to UVB<br />
at 100 mJ/cm 2 .<br />
20<br />
UVB + TR<br />
0<br />
Control<br />
UVB<br />
(0.0001%) (0.0002%)<br />
72.6 mM<br />
Significance **: p
Change language