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Siratro Extract BG - Cosmesi.it

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NIKKO CHEMICALS CO., LTD.<br />

1-4-8 NIHONBASHI-BAKUROCHO, CHUOKU, TOKYO, 103-0002, JAPAN Email: inter@nikkol.co.jp www.nikkol.co.jp<br />

Transparency<br />

NEW<br />

Silver Vine <strong>Extract</strong> <strong>BG</strong>30<br />

Brightening for Stratum Corneum:<br />

Recently <strong>it</strong> was found that decrease in the<br />

skin transparency is induced by protein<br />

carbonylation in the stratum corneum.<br />

Carbonylation makes corneocytes opaque<br />

and enhances their color resulting in “nontransparent<br />

skin” and yellowish or grayish<br />

unhealthy appearance.<br />

Silver Vine <strong>Extract</strong> <strong>BG</strong>30 effectively inhib<strong>it</strong>s<br />

carbonylation of proteins in corneocytes<br />

(stratum corneum cells).<br />

The in vivo evaluation demonstrated that<br />

“skin transparency index” can be improved<br />

by one point w<strong>it</strong>h 1% of Silver Vine <strong>Extract</strong><br />

<strong>BG</strong>30.<br />

Translucent skin<br />

Light is reflected<br />

from inside of the skin<br />

Opaque skin<br />

Decrease in the reflected<br />

light from inside of the skin<br />

In v<strong>it</strong>ro: Inhib<strong>it</strong>ion of protein<br />

carbonylation in corneocytes<br />

(carbonylation level is evaluated by<br />

intens<strong>it</strong>y of green fluorescent dye)<br />

In vivo: Improvement of skin transparency<br />

Period: 28 days.<br />

Dosage of Silver Vine <strong>Extract</strong> <strong>BG</strong>30: 1%.<br />

Results: Skin transparency index (evaluated by<br />

dermatologist) increased by approximately<br />

one point. Color of the skin became brighter<br />

and skin roughness was improved.<br />

0 0.2% 1.0%<br />

Silver Vine <strong>Extract</strong> <strong>BG</strong>30<br />

Carbonylation level (AU)<br />

175<br />

150<br />

125<br />

100<br />

75<br />

50<br />

25<br />

0<br />

0<br />

0.2% 1.0%<br />

Silver Vine <strong>Extract</strong> <strong>BG</strong>30<br />

Skin transparency index<br />

2009-08

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