Siratro Extract BG - Cosmesi.it
Siratro Extract BG - Cosmesi.it
Siratro Extract BG - Cosmesi.it
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NIKKO CHEMICALS CO., LTD.<br />
1-4-8 NIHONBASHI-BAKUROCHO, CHUOKU, TOKYO, 103-0002, JAPAN Email: inter@nikkol.co.jp www.nikkol.co.jp<br />
Transparency<br />
NEW<br />
Silver Vine <strong>Extract</strong> <strong>BG</strong>30<br />
Brightening for Stratum Corneum:<br />
Recently <strong>it</strong> was found that decrease in the<br />
skin transparency is induced by protein<br />
carbonylation in the stratum corneum.<br />
Carbonylation makes corneocytes opaque<br />
and enhances their color resulting in “nontransparent<br />
skin” and yellowish or grayish<br />
unhealthy appearance.<br />
Silver Vine <strong>Extract</strong> <strong>BG</strong>30 effectively inhib<strong>it</strong>s<br />
carbonylation of proteins in corneocytes<br />
(stratum corneum cells).<br />
The in vivo evaluation demonstrated that<br />
“skin transparency index” can be improved<br />
by one point w<strong>it</strong>h 1% of Silver Vine <strong>Extract</strong><br />
<strong>BG</strong>30.<br />
Translucent skin<br />
Light is reflected<br />
from inside of the skin<br />
Opaque skin<br />
Decrease in the reflected<br />
light from inside of the skin<br />
In v<strong>it</strong>ro: Inhib<strong>it</strong>ion of protein<br />
carbonylation in corneocytes<br />
(carbonylation level is evaluated by<br />
intens<strong>it</strong>y of green fluorescent dye)<br />
In vivo: Improvement of skin transparency<br />
Period: 28 days.<br />
Dosage of Silver Vine <strong>Extract</strong> <strong>BG</strong>30: 1%.<br />
Results: Skin transparency index (evaluated by<br />
dermatologist) increased by approximately<br />
one point. Color of the skin became brighter<br />
and skin roughness was improved.<br />
0 0.2% 1.0%<br />
Silver Vine <strong>Extract</strong> <strong>BG</strong>30<br />
Carbonylation level (AU)<br />
175<br />
150<br />
125<br />
100<br />
75<br />
50<br />
25<br />
0<br />
0<br />
0.2% 1.0%<br />
Silver Vine <strong>Extract</strong> <strong>BG</strong>30<br />
Skin transparency index<br />
2009-08