Lifespan and Causes of Death in the Irish Wolfhound - Vetsuisse ...

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6.2 Lifespan Information on lifespan was known for n=1745 individuals. Adjusted for Cohort Bias, n=1423 individuals (583 males / 813 females / 27 unknown) remained. The data contained significantly more females than males (p
6.2.1 Data of Living Dogs Ages at which dogs were still alive were known for n=271 individuals for which no death data were available. Their distribution is rendered in table 6.5: Measure Value (years) Mean age ± SD 8.05 ± 2.17 Minimum 1.84 5% 4.00 1 st quartile 6.84 Median age 8.17 3 rd quartile 9.67 95% 11.00 Maximum 13.50 Table 6.5: Distribution of dogs known to be alive at certain ages 6.2.2 Causes of Death 6.2.2.1 Adjusted for Cohort Bias Causes of Death were known for n=468 individuals. Adjusted for Cohort Bias, n=302 individuals remained (148 males / 153 females / 1 unknown). The gender distribution did not significantly differ from an equal distribution model (p=0.77; chisquare=0.083). Causes of death were classified as discussed in chapter 4.3. Their distribution is given in table 6.6: Cause of Death n % Mean age ± SD All Dogs 302 100.00 7.84 ± 2.66 GDV 25 8.28 7.09 ± 2.69 DCM 56 18.54 7.11 ± 2.31 OS 58 19.21 6.97 ± 1.87 OCa 54 17.88 7.43 ± 2.43 II 32 10.60 5.04 ± 2.70 Accident 42 13.91 4.85 ± 2.57 OGD 35 11.59 6.21 ± 3.75 Table 6.6: Percentual importance of different causes of death Based on these data, cause of death was shown to have a highly significant effect on life expectancy (p
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Aus der Abteilung Tierhaltung und T
Page 3 and 4:
Omnia mors poscit - lex est, non po
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Table of Contents Acknowledgements
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1 Abstract/Summary This study inves
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1.2.3 Own Data A worldwide pedigree
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Due to the frequent bottlenecks dur
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2 Introduction "It is impossible to
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3 Literature Review Several disease
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previous results (Comfort 1960). No
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the average ages were significantly
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3.2 Intrahepatic Portosystemic Shun
Page 23 and 24: Conservative therapy is also indica
Page 25 and 26: mitochondrial hyperplasia, disrupti
Page 27 and 28: there are marked individual differe
Page 29 and 30: 3.3.2 Epizootology Numbers publishe
Page 31 and 32: 2002). On the molecular level, the
Page 33 and 34: 3.4.2 Epizootology In past studies
Page 35 and 36: 3.5.1.3 Diagnosis The history and c
Page 37 and 38: 3.5.2 Epizootology A prospective st
Page 39 and 40: Differential diagnoses include recu
Page 41 and 42: 3.7.1.3 Diagnosis The definite diag
Page 43 and 44: Furthermore, the Utrecht cases also
Page 45 and 46: Figure 3.1: Survival times after fi
Page 47 and 48: have an independent mode of inherit
Page 49 and 50: 3.9.1.5 Prognosis Prognosis for OCD
Page 51 and 52: CU/dl). Of these with low values, 2
Page 53 and 54: 3.12 Miscellaneous 3.12.1 Odds Rati
Page 55 and 56: The disease is clinically character
Page 57 and 58: It is interesting to notice that ev
Page 59 and 60: 4.2.2 The SAS Program Package Stati
Page 61 and 62: 5 Results of Past Studies Revisited
Page 63 and 64: 5.1.4 Causes of Death 5.1.4.1 Influ
Page 65 and 66: 5.2 Analysis of Murphy (1991) ANOVA
Page 67 and 68: 5.2.1.3 Gender Effects As mentioned
Page 69 and 70: 5.2.2.3 Gender Effects No significa
Page 71 and 72: 6.1.2 Inbreeding Four inbreeding co
Page 73: 6.1.3 Geographical Origin Countries
Page 77 and 78: Coefficient R 2 p F Coefficient R 2
Page 79 and 80: Fig. 6.8: Lifespan (GD) of direct p
Page 81 and 82: UC Excluded - Birth Cohorts Merged
Page 83 and 84: Fig. 6.10: 10-Generation Wright's I
Page 85 and 86: The individual and cumulative contr
Page 87 and 88: 6.4 Ancestor Analyses of Diseases P
Page 89 and 90: 6.4.2 Osteogenic Sarcoma 6.4.2.1 Re
Page 91 and 92: 6.4.4 Portosystemic Shunt 6.4.4.1 R
Page 93 and 94: 6.4.5.2 Dog 6844 Given that dog 684
Page 95 and 96: 6.4.5.4 Dog 6636 Dog 6636 (born 195
Page 97 and 98: 7 Discussion 7.1 Lifespan 7.1.1 Lif
Page 99 and 100: findings of the study at hand are i
Page 101 and 102: degree. The fact that average lifes
Page 103 and 104: first-generation progeny. The broad
Page 105 and 106: In this model, the degree of purgin
Page 107 and 108: 7.2.2.5 Present Study No significan
Page 109 and 110: It is interesting to consider what
Page 111 and 112: 7.3 Ethical Considerations 7.3.1 In
Page 113 and 114: 7.3.2 Decreased Lifespan The ethica
Page 115 and 116: (Papazoglou, Monnet et al. 2002). G
Page 117 and 118: While there are currently no heredi
Page 119 and 120: 7.5 Future Research Prospects 7.5.1
Page 121 and 122: 8 References Ackerman, L. (1999). T
Page 123 and 124: Deeb, B. and N. Wolf (1994). "Study
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Kealy, R. D., D. F. Lawler, et al.
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Rothuizen, J. (2002). Molecular Gen
Page 129 and 130:
Walker, H. (1896). Der Irish Wolfho
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ID DR DA DR10 DA10 GR GA GR10 GA10
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