Lifespan and Causes of Death in the Irish Wolfhound - Vetsuisse ...

6.3 Population Genetics of Dogs Born 1965 and After
6.3.1 Inbreeding
The population of dogs born 1965 and after was studied for its genetical composition,
as well as for founders of diseases presumed hereditary. The distribution of
inbreeding coefficients is rendered in table 6.15 and figure 6.9 below. Their
development over time is rendered in fig. 6.10 and 6.11 on the following page.
Inbreeding COI (5) COI (10) COI (20) Meuwissen's IC
up to 0.05 23044 1296 732 762
0.05-0.1 9414 5553 172 63
0.1 to 0.15 5257 11699 330 221
0.15 to 0.2 3552 12591 1980 486
0.2 to 0.25 1078 6512 9559 2320
0.25 to 0.3 777 3614 16044 7162
0.3 to 0.35 209 1442 8396 17290
0.35 to 0.4 51 522 4239 9111
0.4 to 0.45 20 130 1370 4227
0.45 to 0.5 4 37 495 1425
0.5 to 0.55 0 10 69 289
above 0.55 0 0 20 50
Table 6.15: Distribution of inbreeding coefficients in the dogs born post-1964.
COI (n) = Wright's Inbreeding Coefficient over n generations
Inbreeding Coefficients of Dogs Born post-1964 (n=43'406)
25000
22500
20000
Number of Dogs
17500
15000
12500
10000
7500
5000
2500
COI (5)
COI (10)
COI (20)
Meuwissen
0
up to
0.05
0.05-0.1 0.1 to
0.15
0.15 to
0.2
0.2 to
0.25
0.25 to
0.3
0.3 to
0.35
0.35 to
0.4
0.4 to
0.45
0.45 to
0.5
0.5 to
0.55
above
0.55
Inbreeding Coefficient
Fig. 6.9: Distribution of inbreeding coefficients in the dogs born post-1964.
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