Lifespan and Causes of Death in the Irish Wolfhound - Vetsuisse ...

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6.4.3 Gastric Dilation Volvulus 6.4.3.1 Reference Population ID Rank sex YoB Contribution Cumulative Progeny Country 4732 1 m 1939 0.1516 0.1516 10 UK 5838 2 m 1951 0.1453 0.2969 15 US to UK 6636 3 m 1959 0.1205 0.4174 21 UK 4605 4 f 1938 0.0584 0.4758 4 UK 4703 5 f 1939 0.0537 0.5295 4 UK 5538 6 m 1949 0.0452 0.5747 8 US 5184 7 m 1944 0.0341 0.6088 3 UK 4681 8 f 1938 0.0290 0.6378 2 UK 5252 9 f 1945 0.0288 0.6666 2 IRL 6476 10 m 1958 0.0229 0.6895 18 US 6707 11 m 1960 0.0222 0.7117 21 US 4475 12 f 1937 0.0183 0.7300 1 UK 7326 13 m 1964 0.0164 0.7464 23 IRL 6620 14 f 1959 0.0151 0.7615 12 US 6640 15 f 1959 0.0125 0.7740 4 UK 6544 16 m 1958 0.0099 0.7839 7 UK 7052 17 m 1963 0.0096 0.7935 23 IRL 7239 18 f 1964 0.0092 0.8027 5 UK 5045 19 m 1943 0.0091 0.8118 6 US 7051 20 m 1963 0.0089 0.8207 13 IRL Table 6.23: Reference population results for GVD. Reading is analogous to table 6.16. 6.4.3.2 Affected Dogs ID Rank sex YoB Contribution Cumulative Progeny Country 5838 1 m 1951 0.1813 0.1813 13 US to UK 6261 2 m 1955 0.0745 0.2558 9 UK 5561 3 f 1949 0.0694 0.3252 4 UK 5349 4 f 1946 0.0638 0.3890 3 UK 5510 5 f 1948 0.0327 0.4217 2 UK 8251 6 f 1968 0.0252 0.4469 4 IRL 5538 7 m 1949 0.0249 0.4718 10 US 7326 8 m 1964 0.0245 0.4963 17 IRL 7052 9 m 1963 0.0215 0.5178 15 IRL 6476 10 m 1958 0.0203 0.5381 14 US 7002 11 m 1962 0.0177 0.5558 12 UK 6620 12 f 1959 0.0157 0.5715 10 US 6750 13 f 1961 0.0154 0.5869 7 IRL to UK 6661 14 f 1960 0.0150 0.6019 5 IRL to UK 7174 15 f 1963 0.0112 0.6131 3 UK 7051 16 m 1963 0.0110 0.6241 6 IRL 6177 17 f 1955 0.0108 0.6349 1 US 6747 18 m 1961 0.0100 0.6449 5 IRL 6555 19 m 1959 0.0092 0.6541 8 US 8444 20 f 1968 0.0089 0.6630 6 UK Table 6.23: Affected population results for GDV. Reading is analogous to table 6.16. 84
6.4.4 Portosystemic Shunt 6.4.4.1 Reference Population ID Rank sex YoB Contribution Cumulative Progeny Country 5838 1 m 1951 0.2118 0.2118 14 US to UK 5561 2 f 1949 0.0904 0.3022 4 UK 6261 3 m 1955 0.0891 0.3913 10 UK 5349 4 f 1946 0.0673 0.4586 3 UK 5510 5 f 1948 0.0291 0.4877 2 UK 8251 6 f 1968 0.0271 0.5148 7 IRL 7719 7 m 1966 0.0251 0.5399 18 UK 6135 8 f 1954 0.0247 0.5646 11 UK 5538 9 m 1949 0.0205 0.5851 9 US 6476 10 m 1958 0.0203 0.6054 17 US 7617 11 m 1966 0.0161 0.6215 15 IRL 6620 12 f 1959 0.0160 0.6375 11 US 5046 13 m 1943 0.0144 0.6519 3 UK to IRL 7310 14 f 1964 0.0139 0.6658 2 UK 11392 15 m 1973 0.0114 0.6772 26 US 6684 16 m 1960 0.0111 0.6883 15 IRL 5803 17 f 1951 0.0094 0.6977 5 UK 7677 18 m 1966 0.0090 0.7067 11 UK 9386 19 m 1970 0.0079 0.7146 5 US 8444 20 f 1968 0.0076 0.7222 10 UK Table 6.25: Reference population results for PSS. Reading is analogous to table 6.16. 6.4.4.2 Affected Dogs ID Rank sex YoB Contribution Cumulative Progeny Country 6844 1 m 1961 0.0610 0.0610 16 UK 9249 2 m 1970 0.0516 0.1126 20 UK 12386 3 m 1975 0.0426 0.1552 15 UK 10369 4 m 1972 0.0300 0.1852 7 UK 10362 5 f 1972 0.0252 0.2104 6 UK 11392 6 m 1973 0.0239 0.2343 13 US 7978 7 m 1967 0.0181 0.2524 9 UK 7080 8 m 1963 0.0173 0.2697 8 UK 7086 9 f 1963 0.0162 0.2859 4 IRL 7594 10 m 1965 0.0153 0.3012 7 UK 11730 11 m 1974 0.0144 0.3156 15 UK 9840 12 f 1971 0.0142 0.3298 4 US to UK 9861 13 f 1971 0.0141 0.3439 5 UK 12096 14 m 1974 0.0130 0.3569 6 UK 9103 15 f 1970 0.0117 0.3686 2 UK 8153 16 m 1967 0.0116 0.3802 9 US 8382 17 f 1968 0.0116 0.3918 10 US 6533 18 f 1958 0.0108 0.4026 6 UK 6544 19 m 1958 0.0103 0.4129 5 UK 8420 20 m 1968 0.0100 0.4229 8 Sweden Table 6.26: Affected population results for PSS. Reading is analogous to table 6.16. 85
Page 1 and 2:
Aus der Abteilung Tierhaltung und T
Page 3 and 4:
Omnia mors poscit - lex est, non po
Page 5 and 6:
Table of Contents Acknowledgements
Page 7 and 8:
1 Abstract/Summary This study inves
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1.2.3 Own Data A worldwide pedigree
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Due to the frequent bottlenecks dur
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2 Introduction "It is impossible to
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3 Literature Review Several disease
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previous results (Comfort 1960). No
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the average ages were significantly
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3.2 Intrahepatic Portosystemic Shun
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Conservative therapy is also indica
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mitochondrial hyperplasia, disrupti
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there are marked individual differe
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3.3.2 Epizootology Numbers publishe
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2002). On the molecular level, the
Page 33 and 34:
3.4.2 Epizootology In past studies
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3.5.1.3 Diagnosis The history and c
Page 37 and 38:
3.5.2 Epizootology A prospective st
Page 39 and 40: Differential diagnoses include recu
Page 41 and 42: 3.7.1.3 Diagnosis The definite diag
Page 43 and 44: Furthermore, the Utrecht cases also
Page 45 and 46: Figure 3.1: Survival times after fi
Page 47 and 48: have an independent mode of inherit
Page 49 and 50: 3.9.1.5 Prognosis Prognosis for OCD
Page 51 and 52: CU/dl). Of these with low values, 2
Page 53 and 54: 3.12 Miscellaneous 3.12.1 Odds Rati
Page 55 and 56: The disease is clinically character
Page 57 and 58: It is interesting to notice that ev
Page 59 and 60: 4.2.2 The SAS Program Package Stati
Page 61 and 62: 5 Results of Past Studies Revisited
Page 63 and 64: 5.1.4 Causes of Death 5.1.4.1 Influ
Page 65 and 66: 5.2 Analysis of Murphy (1991) ANOVA
Page 67 and 68: 5.2.1.3 Gender Effects As mentioned
Page 69 and 70: 5.2.2.3 Gender Effects No significa
Page 71 and 72: 6.1.2 Inbreeding Four inbreeding co
Page 73 and 74: 6.1.3 Geographical Origin Countries
Page 75 and 76: 6.2.1 Data of Living Dogs Ages at w
Page 77 and 78: Coefficient R 2 p F Coefficient R 2
Page 79 and 80: Fig. 6.8: Lifespan (GD) of direct p
Page 81 and 82: UC Excluded - Birth Cohorts Merged
Page 83 and 84: Fig. 6.10: 10-Generation Wright's I
Page 85 and 86: The individual and cumulative contr
Page 87 and 88: 6.4 Ancestor Analyses of Diseases P
Page 89: 6.4.2 Osteogenic Sarcoma 6.4.2.1 Re
Page 93 and 94: 6.4.5.2 Dog 6844 Given that dog 684
Page 95 and 96: 6.4.5.4 Dog 6636 Dog 6636 (born 195
Page 97 and 98: 7 Discussion 7.1 Lifespan 7.1.1 Lif
Page 99 and 100: findings of the study at hand are i
Page 101 and 102: degree. The fact that average lifes
Page 103 and 104: first-generation progeny. The broad
Page 105 and 106: In this model, the degree of purgin
Page 107 and 108: 7.2.2.5 Present Study No significan
Page 109 and 110: It is interesting to consider what
Page 111 and 112: 7.3 Ethical Considerations 7.3.1 In
Page 113 and 114: 7.3.2 Decreased Lifespan The ethica
Page 115 and 116: (Papazoglou, Monnet et al. 2002). G
Page 117 and 118: While there are currently no heredi
Page 119 and 120: 7.5 Future Research Prospects 7.5.1
Page 121 and 122: 8 References Ackerman, L. (1999). T
Page 123 and 124: Deeb, B. and N. Wolf (1994). "Study
Page 125 and 126: Kealy, R. D., D. F. Lawler, et al.
Page 127 and 128: Rothuizen, J. (2002). Molecular Gen
Page 129 and 130: Walker, H. (1896). Der Irish Wolfho
Page 131: ID DR DA DR10 DA10 GR GA GR10 GA10
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