Alternatives for Brominated Flame Retardants - Miljøstyrelsen

The LD50 for application of melamine on rabbit skin is found in one study
to be slightly larger than 1 mg/kg (1 mg/kg implicates a high risk of adverse
effects on skin of humans).
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One experiment indicates that melamine may be harmful to crustaceans
(LC 100 =56 mg/l), but otherwise the reviewed toxicity data show little aquatic
toxicity.
The available BCF and the pK a values indicate that the bioaccumulation of
this compound is low in the natural pH range (pH 6-8).
The available biodegradation data indicates that this compound is persistent
both under aerobic and anaerobic conditions.
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Antimony trioxide is in the EU classified as "Harmful (Xn)" and must be
labelled with the risk-phrase "Possible risk of irreversible effects" (R40) due
to possible carcinogenicity.
There are epidemiological indications that antimony trioxide causes dermatitis
and has an impact on female reproduction. The substance is teratogenic.
Data from animal experiments seem to indicate that females are more sensitive
concerning developing lung eoplasms than males.
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The toxicity of the substance to algae ranges from harmful to very toxic
(EC 50 100 mg/l), and weight-of-evidence indicates that the substance is not harmful
to fish.
The available data indicates that the substance could be oxidised in the environment.
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No relevant data was found on quinidine carbonate.
No relevant data was found on quinidine carbonate.
If the toxicity of quinidine carbonate is assumed equal (on a molar basis) to
data on quinidine sulfate from [1], the following estimates for quinidine carbonate
can be given:
$UWHPLDVDOLQD(sw): LC 50 (24 h) = 287 mg/l (Artoxkit M) [1]
'DSKLQDPDJQDLC 50 (24 h) = 63 mg/l [1]
The toxicity of quinidine carbonate based on these estimated values indicates
that quinidine carbonate could be harmful to crustaceans.
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