Alternatives for Brominated Flame Retardants - MiljÃ¸styrelsen

More documents

Recommendations

Info

0XWDJHQLFLW\ *HQH0XWDWLRQ &KURPRVRPH$EQRUPDOLWLHV 2WKHU*HQRWR[LF(IIHFWV &DQFHU5HYLHZ ♦Tricresyl phosphate was not mutagenic in Salmonella typhimurium strains TA98, TA100, TA1535, or TA1537, nor did it induce chromosomal aberrations or sister chromatid exchanges in cultured Chinese hamster ovary cells. These in vitro assays were all conducted with and without exogenous metabolic activation. [7]. No relevant data found No relevant data found No relevant data found ♦In 2-year feeding studies there were no evidence of carcinogenic effects of tricresyl phosphate in male or female F344/N rats treated at 75, 150, or 300 ppm. There was no evidence of carcinogenic activity of tricresyl phosphate in male or female B6C3F1 mice treated at 60, 125, or 250 ppm. [7]. 5HSURGXFWLYH7R[LFLW\(PEU\RWR[LFLW\DQG7HUDWRJHQLFLW\ 5HSURGXFWLYH7R[LFLW\ 5HSURGXFWLYH7R[LFLW\FRQW 7HUDWRJHQLFLW\ 2WKHU7R[LFLW\6WXGLHV 7R[LFRNLQHWLFV ♦The reproductive effects of tricresyl phosphate (TCP) were investigated in Long Evans rats . Twelve male rats/dose group were given 0, 100, or 200 mg/kg TCP in corn oil (10 ml/kg body wt) by gavage once/day, 7 days/wk for 56 days prior to breeding and throughout the 10 day breeding period. Twenty four female rats/dose group received 0, 200, or 400 mg/kg TCP in corn oil (10 ml/kg body wt) for 14 days prior to breeding, and throughout breeding, gestation and lactation until the pups were weaned on day 21. Control groups were given corn oil only. The results show that male rats treated with 200 mg/kg TCP had reduced sperm concentration, motility, and velocity (65, 4, and 5% of control, respectively). There was a dose-dependent increase in abnormal sperm morphology in both the 100 mg/kg and 200 mg/kg treated males. TCP did not have an adverse effect on mean testicular wt, but epididymal weights were reduced in the 200 mg/kg dose group males. The % of spermpositive females for TCP-exposed pairs was not different from that of controls. [4]. No relevant data found No relevant data found No relevant data found (FRWR[LFLW\'DWD
$OJDH $QDF\VWLVDHUXJLQRVD EC 50 (96h)>1 mg/l (F) [10] &KORUHOODS\UHQRLGRVD: EC 50 (96h)>1 mg/l (F) [10] 6FHQHGHVPXVSDQQRQLFXV: ♦EC 50 (96h)=1.3 mg/l (F) [10] EC 50 (96h)=3.8 mg/l (F) [10] EC 50 (14d)=1.5 mg/l (F) [10] 6HOHQDVWUXPFDSULFRUQXWXP: EC 50 (96h)>1 mg/l (F) [10] 6WHSKDQRGLVFXVKDQW]VFKLL: ♦EC 50 (96h)=0.29 mg/l (F) [10] (XJOHQDJUDFLOLV: LC 50 (96h)>1.0 mg/l (F) [10] &UXVWDFHDQ )LVK 'DSKQLDPDJQD: EC 50 (24h)=9.1 mg/l (F) [10] EC 50 (24h)>3.2 mg/l (F) [10] ♦EC 50 (48h)=3.6 mg/l (F) [10] 0.10
Page 1 and 2: Working Report 2S2000 Arbejdsrappor
Page 3 and 4: Table of contents 3UHDPEOH 6XPPD
Page 5 and 6: 2 Summary The Danish Environmental
Page 7 and 8: to possible carcinogenicity. The su
Page 9 and 10: på basis af stoffets navn og CAS n
Page 11 and 12: 4 Approach ,QIRUPDWLRQVHDUFK The f
Page 13 and 14: (QYLURQPHQWDO)DWH BCF Aerobic biode
Page 15 and 16: Mobility of TPP and its primary deg
Page 17 and 18: Red phosphorus is often contaminate
Page 19: $SSHQGL[ The appendix contains the
Page 22 and 23: 7ULSKHQ\O3KRVSKDWH &$61R 115-86-6 (
Page 24 and 25: 2WKHU5RXWHV ♦Several studies conc
Page 26 and 27: (FRWR[LFLW\'DWD $OJDH $QNLVWURGHVPX
Page 28 and 29: %&) 2U\]LDVODWLSHV(fw) BCF(18d, con
Page 30: 8 Environmental Fate Database - CHE
Page 33 and 34: 7ULFUHV\O3KRVSKDWH &$61R 1330-78-5
Page 35: 2UDO Oral-rat LD50: 3,500 mg/kg [5]
Page 39 and 40: 2WKHUDTXDWLFRUJDQLVPV %DFWHULD No r
Page 41 and 42: 5HVRUFLQROELVGLSKHQ\OSKRVSKDWH &$6Q
Page 43 and 44: 6ROXELOLW\ZDWHU 3DUWLWLRQ&RHIILFLHQ
Page 45 and 46: 7R[LFRNLQHWLFV No relevant data fou
Page 48 and 49: 3KRVSKRQLFDFLG K\GUR[\PHWK\OFDUEDQ\
Page 50 and 51: )ODPPDELOLW\ ([SORVLYLW\ 2[LGLVLQJS
Page 52 and 53: (QYLURQPHQW The available data is i
Page 54 and 55: Aluminium trihydroxide &$61R 21645-
Page 56 and 57: 2UDO Because aluminium is only spar
Page 58 and 59: 2WKHU7R[LFLW\6WXGLHV No relevant da
Page 60: 1 Chemfinder: http://www.chemfinder
Page 63 and 64: 0DJQHVLXPK\GUR[LGH &$61R 1309-42-8
Page 65 and 66: ,UULWDWLRQRI5HVSLUDWRU\7UDFW 6NLQ6H
Page 67: 5HIHUHQFHV 1 Chemfinder: http://www
Page 70 and 71: Ammonium Polyphosphate &$61R 68333-
Page 72 and 73: 5HSURGXFWLYH7R[LFLW\(PEU\RWR[LFLW\D
Page 75 and 76: 5HG3KRVSKRUXV &$6QXPEHU 'DWDFRPSLOD
Page 77 and 78: 0ROHFXODU:HLJKWJPRO Depending on cr
Page 79 and 80: ,QKDODWLRQ ♦9 out of 10 rats died
Page 81 and 82: &UXVWDFHDQFRQW Yellow phosphorus: *
Page 83: 6 IUCLID CD rom, European Commissio
Page 86 and 87:
Zinc Borate &$61R 1332-07-6 (,1(&61
Page 88 and 89:
2UDO ,QKDODWLRQ 'HUPDO No relevant
Page 90 and 91:
&RQFOXVLRQ +HDOWK There is not suff
Page 92 and 93:
0HODPLQH &$6QXPEHU 'DWDFRPSLODWLRQH
Page 94 and 95:
'HFRPSRVLWLRQ7HPSHUDWXUH°& No rele
Page 96 and 97:
2UDO Chronic feeding tests have bee
Page 98 and 99:
$HURELFELRGHJUDGDWLRQ BOD 5 (20 °C
Page 101 and 102:
$QWLPRQ\WULR[LGH &$6QXPEHU 'DWDFRPS
Page 103 and 104:
9DSRXU'HQVLW\DLU No relevant data
Page 105 and 106:
,QKDODWLRQ Three groups of 8 month
Page 107 and 108:
&UXVWDFHDQ )LVK 'DSKQLDPDJQD: ♦EC
Page 109:
4XLQLGLQHFDUERQDWH &$6QXPEHUQRWDYDL
show all

Alternatives for Brominated Flame Retardants - MiljÃ¸styrelsen

Create successful ePaper yourself

Delete template?

Save as template?