From Protein Structure to Function with Bioinformatics.pdf

11 Function Predictions of Structural Genomics Results 291Tan K, Li H, Zhang R, et al. (2008) Structures of open (R) and close (T) states of prephenatedehydratase (PDT) - implication of allosteric regulation by L-phenylalanine. J Struct Biol162:94–107Teichmann SA, Murzin AG, Chothia C (2001) Determination of protein function, evolution andinteractions by structural genomics. Curr Opin Struct Biol 11:354–363Todd A, Orengo C, Thornton JM (2001) Evolution of function in protein superfamilies, from astructural perspective. J Mol Biol 307:1113–1143Watson JD, Sanderson S, Ezersky A, et al. (2007) Towards fully automated structure-based functionprediction in structural genomics: a case study. J Mol Biol 367:1511–1522Whisstock JC, Lesk AM (2003) Prediction of protein function from protein sequence and structure.Q Rev Biophys 36:307–340Wu R, Skaar EP, Zhang R, et al. (2005) Staphylococcus aureus IsdG and IsdI, heme-degradingenzymes with structural similarity to monooxygenases. J Biol Chem 280:2840–2846Yooseph S, Sutton G, Rusch DB, et al. (2007) The Sorcerer II Global Ocean Sampling expedition:expanding the universe of protein families. PLoS Biol 5:e16Zhang S, Wilson DB, Ganem B (2000) Probing the catalytic mechanism of prephenate dehydrataseby site-directed mutagenesis of the Escherichia coli P-protein dehydratase domain.Biochemistry 39:4722–4728