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A study of the priority substances of the Water Framework Directive ...

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..:::::::::: appendix c<br />

..:::102<br />

APPENDIX C<br />

Short list <strong>of</strong> words and terms<br />

Acute oral LD50: Acute lethal dose for 50 percent<br />

<strong>of</strong> a group <strong>of</strong> test animals (rats) within a<br />

defined period <strong>of</strong> time, <strong>of</strong>ten 24 hours. The dose<br />

is normally given in micrograms per gram body<br />

weight.<br />

BCF: Bio-concentration factor. Defined as <strong>the</strong><br />

concentration <strong>of</strong> a chemical in an organism<br />

(divided by <strong>the</strong> concentration in a reference<br />

compartment (e.g. food, surrounding water)).<br />

ClassLab: "Harmonised Classifications and<br />

Labelling for Substances, refers to <strong>the</strong><br />

Norwegian St<strong>of</strong>flisten. St<strong>of</strong>flisten has some<br />

information that is specific to Norway.<br />

EC50: Effect concentration. The concentration<br />

that gives effects on 50 percent <strong>of</strong> test animals<br />

within a given period <strong>of</strong> time.<br />

Half life: Half life (or DT50) is <strong>the</strong> time it takes<br />

for half <strong>the</strong> amount <strong>of</strong> a chemical to disappear.<br />

This may happen due to evaporation, hydrolysis,<br />

photo degradation, chemical degradation,<br />

degradation by bacteria etc. When using values<br />

for half life it should be taken into considera-<br />

A <strong>study</strong> <strong>of</strong> <strong>the</strong> <strong>priority</strong> <strong>substances</strong> <strong>of</strong> <strong>the</strong> <strong>Water</strong> <strong>Framework</strong> <strong>Directive</strong><br />

TA-2140/2005<br />

tion that chemicals which are easily degraded by<br />

for instance sunlight may be very persistent in<br />

groundwater or sediments, and that a chemical<br />

may be degraded via several routes simultaneously.<br />

Thus different half life values are given for each<br />

substance for depending on where <strong>the</strong> chemical<br />

is released and type <strong>of</strong> degradation.<br />

LC50: Lethal concentration (usually in water)<br />

for fish or invertebrates, <strong>the</strong> concentration<br />

required to kill 50 percent <strong>of</strong> a group <strong>of</strong> fish or<br />

invertebrates in a given time (normally 24 - 96<br />

hours)<br />

Log Kow:Log Octanol-<strong>Water</strong> Partitioning<br />

Coefficient. High Log Kow indicates a compound<br />

which will preferentially partition into<br />

soil organic matter ra<strong>the</strong>r than water.<br />

NOEL/NOAEL: No observed effect level / No<br />

observed adverse effects level. The highest<br />

amount <strong>of</strong> a substance that can be administered<br />

without any effects on <strong>the</strong> test animals.

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