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In Pursuit of the Gene

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298 ¨ NOTES TO PAGES 36–42<br />

35. Letter from Galton to George Howard Darwin, May 17, 1876, in Ruth<br />

Schwartz Cowan, “Francis Galton’s Statistical Ideas: The <strong>In</strong>fluence <strong>of</strong> Eugenics,”<br />

Isis, 63 (1972): 518.<br />

36. Letter from Galton to George Darwin, Jan. 5, 1877, in Pearson, Galton, 3B:465.<br />

37. Galton introduced a clever extension <strong>of</strong> <strong>the</strong> normal <strong>the</strong>ory that required a revamped<br />

quincunx to illustrate. See Stigler, History <strong>of</strong> Statistics, 275–281, for a detailed<br />

explanation <strong>of</strong> <strong>the</strong> <strong>the</strong>ory.<br />

38. Cowan, “Galton’s Statistical Idea,” 521 n. 44.<br />

39. Galton, “Opening Address,” 507.<br />

40. For example, <strong>the</strong> “1” in <strong>the</strong> upper right corner <strong>of</strong> <strong>the</strong> graph indicates that<br />

<strong>the</strong>re was 1 adult child in <strong>the</strong> range between 4 and 5 inches above average height<br />

born to mid-parents who were between 3 and 4 inches above average.<br />

41. Francis Galton, Memories <strong>of</strong> My Life (London: Methuen and Co., 1908), 302.<br />

42. Letter from Galton to Tertius, Nov. 3, 1840, in Pearson, Galton, 1:144<br />

43. Pearson, Galton, 1:302–303.<br />

44. Francis Galton, “Regression toward Mediocrity in Stature,” Miscellanea <strong>of</strong> <strong>the</strong><br />

Journal <strong>of</strong> <strong>the</strong> Anthropological <strong>In</strong>stitute <strong>of</strong> Great Britain 15 (1886): 255; and again in Galton,<br />

Natural <strong>In</strong>heritance, 102<br />

45. Galton, “Opening Address,” 507<br />

46. Galton, “Regression toward Mediocrity,” 253<br />

47. Ibid., 256.<br />

48. Ibid, 253.<br />

49. Galton’s error had been to group toge<strong>the</strong>r in each height class a variety <strong>of</strong><br />

people from different ancestries. Under this procedure, a significant number <strong>of</strong> exceptionally<br />

tall (or short) people who came from families <strong>of</strong> unexceptional height<br />

and whose exceptional height was due to nutrition or o<strong>the</strong>r environmental factors<br />

that were not heritable were grouped toge<strong>the</strong>r with people who carried tall genes.<br />

It was simply not true that exceptional parent types would necessarily have less exceptional<br />

children, or that <strong>the</strong> plants with large seeds would give rise to plants with<br />

seeds <strong>of</strong> smaller size. Contrary to Galton’s belief, <strong>the</strong> <strong>of</strong>fspring <strong>of</strong> a marriage <strong>of</strong> tall<br />

families would, on average, be as tall as <strong>the</strong>ir parents, and likewise, large seeds derived<br />

from a single ancestral line would have given rise to progeny peas that were,<br />

on average, as large as <strong>the</strong>ir parental seeds. Fur<strong>the</strong>rmore, if tall men and women<br />

were selected out over a period <strong>of</strong> generations (until <strong>the</strong>y were homozygous for<br />

<strong>the</strong> genes coding for increased height), <strong>the</strong>re would ultimately be no regression at<br />

all in height. Theoretically, selective breeding can create a race <strong>of</strong> giants.

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