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In Pursuit of the Gene

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70 ¨ PANGENES<br />

he took a position as a high school teacher in Amsterdam, and spent summers<br />

at <strong>the</strong> University <strong>of</strong> Würzburg, where he conducted a series <strong>of</strong> elegant<br />

experiments on plant movement under <strong>the</strong> supervision <strong>of</strong> <strong>the</strong> great German<br />

plant physiologist Julius Sachs, a diehard reductionist and one <strong>of</strong> <strong>the</strong><br />

principal promoters <strong>of</strong> <strong>the</strong> modern mechanistic approach to plant physiology.<br />

<strong>In</strong> Würzburg, home to Virchow and Haeckel and <strong>the</strong> richest vein <strong>of</strong><br />

German cell biology, De Vries’s sense <strong>of</strong> <strong>the</strong> world <strong>of</strong> biology and his possible<br />

role in it began to take shape. Over a period <strong>of</strong> three summers with<br />

Sachs, De Vries wrote several beautiful papers.<br />

It was De Vries’s good fortune that Charles Darwin shared his somewhat<br />

obscure interest in <strong>the</strong> nature <strong>of</strong> plant movement. <strong>In</strong> 1875 Darwin<br />

sent De Vries a complimentary copy <strong>of</strong> his new book, On <strong>the</strong> Movements and<br />

Habits <strong>of</strong> Climbing Plants, which contained no fewer than five glowing references<br />

to De Vries and his excellent studies! Exceedingly polite, De Vries<br />

wrote back that his papers “should not be entitled to such honor as you bestow<br />

on <strong>the</strong>m.” 1 This led to ano<strong>the</strong>r exchange <strong>of</strong> letters in which Darwin,<br />

with his characteristic blend <strong>of</strong> scientific generosity and self-interest, gently<br />

tried to steer De Vries in <strong>the</strong> direction that Darwin himself found most interesting.<br />

<strong>In</strong>spired by Darwin’s high praise and <strong>the</strong> generally positive reception<br />

<strong>of</strong> his work, De Vries accepted a full-time position in a Prussian university,<br />

which he hoped would eventually lead him to a full-fledged academic<br />

career. After enduring two years in <strong>the</strong> intensely hierarchical German university<br />

system, De Vries leaped at <strong>the</strong> opportunity to return to Amsterdam<br />

as an instructor at <strong>the</strong> newly formed A<strong>the</strong>naeum University. 2 A year later,<br />

in <strong>the</strong> fall <strong>of</strong> 1878, at <strong>the</strong> extraordinarily young age <strong>of</strong> 29, he was made a<br />

pr<strong>of</strong>essor.<br />

During <strong>the</strong> summer before he assumed his pr<strong>of</strong>essorship, De Vries paid<br />

a final visit to Würzburg, where he was introduced to Darwin’s youngest<br />

son, Francis. Through Francis, De Vries saw <strong>the</strong> means to renew his acquaintance<br />

with <strong>the</strong> old man himself and in so doing burnish his already<br />

brilliant debut in academic science. Several weeks later, with invitations to<br />

visit <strong>the</strong> cream <strong>of</strong> British botanists in hand, De Vries left for England. Once<br />

<strong>the</strong>re, he quickly managed to get himself invited to dinner with <strong>the</strong> influ-

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