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Traitement des carcinoses péritonéales d'origine colo-rectale. Quoi ...

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Table 6. Prognostic Impact of Clinical Factors on Overall Survival by Univariate Analysis<br />

Therapeutic Factor No.<br />

Analyzed<br />

months to 42 months, but that effect was not replicated<br />

when the analysis was adjusted based on the center.<br />

However, it is reasonable to assume that experience may<br />

provide better patient selection, surgical expertise, and<br />

postoperative management. A learning curve already<br />

had been reported by several authors. Moran reported a<br />

decreased mortality rate from 18% down to 3%, 21 The<br />

Netherlands Cancer Institute reported a decrease in<br />

mortality from 8% to 4%, 22 and Yan et al reported a<br />

decrease from 7% to 1%. 23 All interventional complex<br />

procedures have an inherent risk, and experience<br />

undoubtedly diminishes but can never abolish this<br />

risk. 24<br />

Median<br />

survival,<br />

mo<br />

Treatment of Peritoneal Carcinomatosis/Glehen et al<br />

3-Year<br />

Survival,<br />

%<br />

Preoperative systemic chemotherapy<br />

Yes 633 31 43 30<br />

No 580 45 55 43<br />

5-Year<br />

Survival,<br />

%<br />

Synchronous resection of liver metastasis .003<br />

Yes 117 21 34 25<br />

No 955 36 51 39<br />

CCR category

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