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Interior 2_2005.qxd - Oftalmologia.ro

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OFTALMOLOGIA 2 - 2005<br />

PRINCIPII DE TRATAMENT<br />

ALE ARSURILOR OCULARE ~N<br />

LUMINA CONCEPTULUI DE<br />

SUPRAFA}| OCULAR| {I<br />

CELULE STEM LIMBICE<br />

V. POTOP, MARIETA DUMITRACHE<br />

REZUMAT<br />

Conceptul de suprafa\` ocular` define]te interdependen\a func\ional` existent`<br />

[ntre cele dou` epitelii nekeratinice ale corneei ]i conjunctivei. Celulele stem limbice<br />

asigur` regenerarea epiteliului cornean survenit` [n urma diferitelor injurii. Aplicarea acestor<br />

concepte a permis p<strong>ro</strong>grese importante [n tratamentul arsurilor oculare.<br />

CUVINTE CHEIE:<br />

• suprafa\` ocular`,<br />

• celule stem limbice,<br />

• ulcera\ii corneene sterile,<br />

• arsuri chimice.<br />

ABSTRACT<br />

The term ocular surface emphasizes the functional interdependence of the<br />

nonkeratinizing epithelium of cornea and conjunctiva. The limbal stem cells are responsable<br />

for replacement of corneal epithelium following ocular surface injuries. Over the past<br />

decades important advances in the management of chemical injury have occured based<br />

on the application of theories on ocular surface and limbal stem cells .<br />

KEY WORDS:<br />

• ocular surface,<br />

• limbal stem cells,<br />

• sterile corneal ulceration,<br />

• chemical injuries.<br />

Din punct de vedere anatomic suprafata globului ocular prezint` limite precise ce par<br />

a separa structuri diferite histologic. Limbul scle<strong>ro</strong>cornean separa intre ele epiteliile<br />

corneean si cel conjunctival. Epiteliul cornean este de tip stratificat scuamos nekeratinizat<br />

compus din 5-6 straturi celulare si lipsit de celule caliciforme. El se afla intr-un p<strong>ro</strong>ces de<br />

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