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online online @sciencecareers.org ThereÕs only one Science Careers Advertising For full advertising details, go to ScienceCareers.org and click For Employers, or call one of our representatives. Tracy Holmes Worldwide Associate Director Science Careers Phone: +44 (0) 1223 326525 THE AMERICAS E-mail: advertise@sciencecareers.org Fax: 202-289-6742 Tina Burks East Coast/West Coast/South America Phone: 202-326-6577 Allyson Rosen Midwest/Canada/Corporate Phone: 202-326-6578 Marci Gallun Sales Administrator Phone: 202-326-6582 Online Job Posting Questions Phone: 202-312-6375 EUROPE/I NDIA/AUSTRALIA/ NEW ZEALAND/REST OF WORLD E-mail: ads@science-int.co.uk Fax: +44 (0) 1223 326532 Lucy Nelson Phone: +44 (0)1223 326527 Kelly Grace Phone: +44 (0) 1223 326528 JAPAN Yuri Kobayashi Phone: +81-(0)90-9110-1719 E-mail: ykobayas@aaas.org CHINA/KOREA/SINGAPORE/ TAIWAN/THAILAND Ruolei Wu Phone: +86-1367-1015-294 E-mail: rwu@aaas.org All ads submitted for publication must comply with applicable U.S. and non-U.S. laws. Science reserves the right to refuse any advertisement at its sole discretion for any reason, including without limitation for offensive language or inappropriate content, and all advertising is subject to publisher approval. Science encourages our readers to alert us to any ads that they feel may be discriminatory or offensive. ScienceCareers.org www.rom.on.ca The Royal Ontario Museum (ROM) is Canada’s pre-eminent international museum and houses some of Canada’s most important collections in both Natural History and World Cultures. The Department houses Canada’s largest mineral and gem collections, an important meteorite collection, and a comprehensive petrology collection. Mineralogist Natural History Department The ROM invites applications from world-class scholars for the position of the Teck Chair in Mineralogy, to conduct field and collections-related research, and the strategic acquisition of new specimens, and to present these holdings through future exhibitions, gallery rotations and public programming. The Teck Endowed Chair in Mineralogy was established in 2007 thanks to the generous support of Teck Resources Limited. As a leading contributor to the new, public-facing Centre of Discovery for Earth and Space, the successful candidate will have demonstrated skills in transfer of scientific concepts and information in a manner that engages visitors to the museum and the general public, on site and on-line. The successful applicant will be expected to: provide dynamic leadership for the Earth Sciences staff; develop a program of externally funded scholarly research and publications; curate and continue building the disciplinary collection of minerals; and have demonstrated ability and interest in the development and rotation of new permanent galleries and major exhibitions, traveling exhibits, science education, and public engagement. Applicants must have a Ph.D. in mineralogy, and be well versed in the geological sciences; have a record of scholarly publication in peer-reviewed journals; be qualified for cross-appointment to the University of Toronto; and be eligible for NSERC funding in support of research (i.e., a proven record of successful grant applications). Experience in a museum or equivalent environment is preferable. Salary and years in rank are commensurate with experience, as stipulated in the Collective Agreement between the ROM and ROM Curatorial Association. Applications will be accepted until 5:00 p.m., March 29, 2013. Applicants should provide a curriculum vitae, a summary of their research, and an outline of their proposed program of research, and arrange to have three confidential letters of recommendation sent on their behalf, to: Mara Gunner, Human Resources Coordinator, Human Resources Department, Royal Ontario Museum, 100 Queen’s Park, Toronto, Ontario, Canada, M5S 2C6. Fax: 416-586-5827. All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority. STAY INFORMED! STAY CONNECTED! Get more from your AAAS membership Are you currently registered to receive e-mails from AAAS and Science? E-mail is the primary way that AAAS communicates with our members about AAAS programs, new member benefits, invitations to special events, and, of course, the latest news and research being published in Science. Sign up today to receive e-mails from AAAS and ensure that you are getting themostoutofyourmembershipandScience subscription. * To get started visit: promo.aaas.org/stayconnected You’ll need your AAAS Member number. Find it above your name on your Science mailing label. Don’t miss a thing. Sign up for e-mail communications from AAAS today! *AAAS follows CAN-SPAM and European Safe Harbor guidelines for protecting your privacy. We will never sell your e-mail address and you can opt-out of receiving e-mails at any time.
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CONTENTS EDITORIAL 737 Designing Sc
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736 EDITED BY STELLA HURTLEY The Bu
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CREDITS: (TOP LEFT) TOM KOCHEL; (RI
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CREDIT: WIKIMEDIA COMMONS and orbit
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CREDITS (TOP TO BOTTOM): EOS/UNIVER
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CREDIT: TITUS ET AL., SCIENCE TRANS
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CREDITS (TOP TO BOTTOM): ISTOCKPHOT
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CREDIT: NATIONAL SCIENCE FOUNDATION
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CREDITS (CLOCKWISE FROM TOP LEFT):
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Sensing cytosolic danger ture capit
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TECHNICAL COMMENT 757-c Fig. 2. Rel
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TECHNICAL COMMENT 757-d values ment
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policy ideas” could be rectifi ed
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ARMS CONTROL Beyond Arms-Control Mo
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CREDIT: K. SUTLIFF/SCIENCE IMMUNOLO
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A Field et al. B Partial modern tre
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depend on the binding strength of t
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CREDIT: K. SUTLIFF/SCIENCE A Restri
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increasing the accuracy of the meas
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Structural Biological Materials: Cr
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increasing toughness. These methods
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Fig. 6. cGAS binds to DNA in the cy
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How do we answer this trilemma? As
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(9). For n = 3, where we used three
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Fig. 2. Schematic and characterizat
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computation in the presence of erro
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REPORTS greatly eases the requireme
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dynamically, therefore, Sr3Ru2O7 ca
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16. N. P. Ong, Phys. Rev. B 43, 193
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low-energy break in IC 443 and 21s
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32. T. Kamae, N. Karlsson, T. Mizun
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ferent structures rather than the e
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Fig. 1. Fish behavioral response to
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charge distribution, and DNA bindin
Page 90 and 91: ecause the efficiency of transcript
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Page 96 and 97: targeting ~40.5% exons of genes in
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Page 100 and 101: of the MS spectra revealed two ions
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Page 104 and 105: Fig. 3. PE is a necessary condition
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