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Dog Owner's Home Veterinary Handbook.pdf - Mr. Walnuts

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360 •DOG OWNER’S HOME VETERINARY HANDBOOK<br />

<strong>Dog</strong>s who recover may exhibit a posttraumatic syndrome that can include<br />

seizures, behavior changes, head tilt, and blindness.<br />

Brain Diseases<br />

ENCEPHALITIS (BRAIN INFECTION)<br />

Encephalitis is an inflammation of the brain. Symptoms include fever, depression,<br />

behavior and personality changes (especially aggression), uncoordinated<br />

gait, seizures, stupor, and coma.<br />

Canine distemper is the most common cause of encephalitis in dogs. Signs<br />

develop two to three weeks after the onset of the disease. Other causes of viral<br />

encephalitis include rabies, pseudorabies, and herpesvirus. Rabies is a very<br />

serious disease, but with present-day vaccination programs the disease is not<br />

common among domesticated animals. Canine herpesvirus produces an<br />

encephalitis in puppies younger than 2 weeks of age.<br />

Bacterial encephalitis is caused by organisms that enter the brain via the<br />

circulatory system, such as bacterial endocarditis, or by direct extension from<br />

an infected sinus, nasal passage, or an abscess in the head or neck. Migrating<br />

foreign bodies such as porcupine quills or grass awns may get into the central<br />

nervous system. Fungal brain infections (caused by cryptococcosis, blastomycosis,<br />

or histoplasmosis) are rare causes of encephalitis, as are protozoan infections.<br />

Tick-borne rickettsial diseases, notably Rocky Mountain spotted fever<br />

and canine ehrlichiosis, are infrequent causes. These diseases may also<br />

involve the spinal cord.<br />

Postvaccination encephalitis is rare with modern vaccines. It was most<br />

likely to occur when modified live virus distemper vaccine was administered<br />

at the same time as modified live parvovirus vaccine in puppies less than 6 to<br />

8 weeks old. This is not usually seen with current vaccines and vaccination<br />

schedules.<br />

Lead encephalitis is seen primarily in young dogs who chew on materials<br />

that contain lead, such as paint and drywall, especially in older buildings.<br />

Lead alters brain metabolism and causes inflammation and swelling. Central<br />

nervous system signs are often preceded by vomiting, diarrhea, or constipation.<br />

The diagnosis is confirmed by an elevated blood lead level.<br />

Meningitis is an infection of the surface of the brain and spinal canal. It is<br />

caused by infected bite wounds about the head and neck and bacterial infections<br />

that travel to the brain from the sinuses, nasal passages, or middle ears.<br />

Aseptic meningitis is a nonbacterial disease of unknown cause. It affects<br />

large-breed dogs 4 to 24 months of age.<br />

The diagnosis of encephalitis or meningitis is based on analysis of cerebrospinal<br />

fluid obtained by spinal tap. Serologic tests may identify the cause of<br />

the inflammation.

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