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Dog Owner's Home Veterinary Handbook.pdf - Mr. Walnuts

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504 •DOG OWNER’S HOME VETERINARY HANDBOOK<br />

when they ingest colostrum that contains antibodies designed to attack their<br />

red blood cells. These antibodies are manufactured by the dam only if she has<br />

been previously sensitized to the sire’s blood group antigens—which can occur<br />

when fetal cells of a different blood type cross the placenta.<br />

Affected puppies are born healthy and start to nurse vigorously. But once<br />

they drink the dam’s colostrum, the dam’s antibodies begin to destroy their<br />

red blood cells. They start to show clinical signs within hours to days, stop<br />

nursing, and fail to thrive. They develop hemolytic anemia within one to two<br />

days after birth and some or all will die.<br />

Early clinical signs of the disease include dark red-brown urine, weakness,<br />

failure to thrive, and jaundice. Death can occur in 24 hours. Blood tests, urinalysis,<br />

and blood typing can diagnosis the condition.<br />

Treatment: As soon as you suspect hemolytic anemia, stop all nursing and<br />

notify your veterinarian. The puppies may require blood transfusions from a<br />

compatible donor to restore their red cells. Puppies from subsequent litters<br />

should not be allowed to receive colostrum from the dam, unless the sire and<br />

dam have compatible blood types.<br />

UMBILICAL (NAVEL) INFECTION<br />

A common predisposing factor in navel infection is severing the umbilical<br />

cord too close to the abdominal wall. This leaves no stump to wither up and<br />

separate cleanly. Other possible causes are a dam with dental disease who<br />

transmits bacteria when she severs the umbilical cord, and an unclean whelping<br />

box contaminated by urine and stools. An infected navel looks red and<br />

swollen and may drain pus or form an abscess.<br />

There is a direct communication between the umbilical cord and the liver,<br />

which makes even a low-grade umbilical infection potentially dangerous.<br />

Untreated, puppy septicemia is likely.<br />

Treatment: At the first indication of navel infection, seek veterinary<br />

attention for antibiotic treatment. If one puppy has an umbilical infection, it<br />

may also be present in other puppies in the litter.<br />

Iodine applied to the navel stump at birth as a preventive measure reduces<br />

the likelihood of umbilical infection.<br />

PUPPY SEPTICEMIA<br />

Blood-borne infections in young puppies are caused by bacteria that gain<br />

entrance via the respiratory and gastrointestinal tracts. They occur in puppies<br />

5 to 12 weeks of age. At this age maternal antibodies are in decline and<br />

immunity acquired through vaccinations is not as strong as it eventually will<br />

be. This creates a window of vulnerability.<br />

Very important contributing factors include overcrowding, chilling, poor<br />

nutrition, unsanitary whelping quarters, a heavy burden of intestinal para-

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