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Transcriptional Characterization of Glioma Neural Stem Cells Diva ...

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Appendix C<br />

Long ncRNAs<br />

We detected 25 differentially expressed long non-coding RNAs. Several <strong>of</strong> these<br />

display an expression pattern similar to a neighbouring protein-coding gene,<br />

including cancer-associated genes DKK1 and CTSC [113,461,551] and devel-<br />

opmental regulators IRX2, SIX3 and ZNF536 [412], suggesting that they may<br />

be functional RNAs regulating nearby genes [372] or represent transcription<br />

from active enhancers [230].<br />

273

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