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Transcriptional Characterization of Glioma Neural Stem Cells Diva ...

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C. Long ncRNAs Appendix<br />

Table C.1: Differentially expressed non-coding RNAs.<br />

Tag Accession Description In gene desert? PubMedID(s) Differential expression results Normalised tag counts<br />

log 2(F C) p-value FDR G144ED G144 G166 G179 CB541 CB660<br />

HOTAIRM1, a ncRNA from the<br />

HOXA locus. There is evidence<br />

CCGCCTTAATAAATGTA BC031342<br />

No 19144990 Inf 7.9E-10 4.3E-06 174.7 158.7 129.8 206.3 0.0 0.0<br />

that it might regulate HOXA gene<br />

expression.<br />

NEAT1, a ncRNA involved in<br />

TACATAATTACTAATCA NR_028272 paraspeckle formation and regu- Yes 20137068; 21170033 4.32 1.6E-06 2.2E-03 123.4 627.4 775.4 1927.1 18.5 91.8<br />

lated during NS cell differentiation.<br />

CDKN2BAS, an antisense transcript<br />

to CDKN2B that appears<br />

TGGATAAACAAAATGAA NR_003529 to function in Polycomb-mediated No 18185590; 20541999 Inf 1.4E-05 1.3E-02 18.0 33.6 125.8 0.0 0.0 0.0<br />

repression <strong>of</strong> tumor suppressors<br />

CDKN2A and CDKN2B.<br />

Transcript from the opposite strand<br />

TATCCCCAAATAAACAA NR_015382<br />

No None 4.42 3.2E-05 2.4E-02 151.4 123.2 332.4 135.3 9.3 9.4<br />

<strong>of</strong> CD27.<br />

Transcript from the opposite strand<br />

ATGGCACCATATTGTGT NR_015377<br />

No None -7.08 2.5E-05 2.0E-02 0.0 0.0 2.2 0.0 136.9 58.3<br />

<strong>of</strong> PAX8.<br />

Transcript from the opposite strand<br />

CCTGACCCTGCATCCCT BC013229<br />

No None Inf 1.4E-04 7.5E-02 1.7 0.0 36.9 68.3 0.0 0.0<br />

<strong>of</strong> MCF2L2.<br />

Transcript from the opposite strand<br />

TAGAACGGTGTTCCTCC BM977209<br />

No None Inf 1.7E-05 1.5E-02 0.0 0.0 121.6 24.7 0.0 0.0<br />

<strong>of</strong> TXNRD1.<br />

Transcript from CDKN2B intron<br />

ACAAACAAAAGCCTTCC DB099927<br />

No None Inf 1.4E-05 1.3E-02 41.9 105.5 51.8 0.0 0.0 0.0<br />

(sense strand).<br />

Transcript from gene desert near<br />

ATTACATTTATGTCCTT BC015429 DKK1. Correlated with DKK1 ex- Yes None Inf 2.8E-09 1.1E-05 0.0 0.0 389.5 18.0 0.0 0.0<br />

pression.<br />

TAACTGATCCTTAGATA BQ957425 Transcript from gene desert. Yes None Inf 2.0E-04 9.9E-02 0.0 0.0 66.8 30.8 0.0 0.0<br />

GAAACATTCCAAACCTA AK094154 Transcript from gene desert. Yes None Inf 1.3E-10 9.9E-07 0.0 0.0 328.5 243.9 0.0 0.0<br />

CAAATAAACTTTATACC BC063641 Transcript downstream <strong>of</strong> PRRG4. No None 7.53 2.4E-11 2.3E-07 4.2 68.0 267.3 1381.8 0.0 5.9<br />

Transcript between CTSC and<br />

GCTTTATTTTTTCTGCT BC038205 GRM5. Correlated with CTSC Yes None 7.46 5.4E-07 8.7E-04 54.0 96.2 49.6 126.3 0.0 1.0<br />

expression.<br />

GAGCCCAGACTAGATGG BF031226 Transcript from gene desert. Yes None Inf 3.9E-05 2.8E-02 1.4 0.0 30.7 99.7 0.0 0.0<br />

274<br />

Yes 12082533; 15872005 -Inf 3.5E-07 6.3E-04 0.0 0.0 0.0 0.0 21.8 283.9<br />

The tag is in last intron <strong>of</strong><br />

ncRNA NCRMS, perhaps detecting<br />

an NCRMS is<strong>of</strong>orm. NCRMS might<br />

be a host transcript for mir-1251<br />

and mir-135a-2. The tag also coincides<br />

with a SINE repeat.<br />

AAATATTAGTTTTTCTT CX868766

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