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PM History/2 - Legacy Tobacco Documents Library

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PBfI history/6A<br />

--INFLUENCE OF HYGROSCOPIC AGENTS IN CIGS, LARYNGO3COPE 2/35 by<br />

Dr . Frederick R . F1inn : It's hard to isolate objective symptoms that<br />

cannot be attributed to some other pathologic conditions + in assessing<br />

effect of smkg on mucous membrane of nose & throat, no way to express<br />

degree of congestion . . .this study suggested by work of Mulinos<br />

& Osborne//bear in mind eo le smoke in differ nt w , e .g ., if you<br />

smoke down to the stub, more ea irritatin each.dr~pickQd 1'O" ._0<br />

mk atients usin o, brands w h rosco ic a ent symptoms associa<br />

ed w sm g& t eir cigs were rep ace w ose using DI-GLYCOL<br />

& instructed to smoke only these ; on avg they had been smkg 12 yrs &<br />

28 cigs a day . . .AT OUTSET : nearly 3/4 showed congested larynx & pharynx,<br />

2/3 had coughs, 20% had heart palpitation & 71- tongue irrtation . . . after<br />

smk~ DI-GLY cigs for 3-~ wk~ con~estion disappeared in nearly twothird~-<br />

ose w eem & s iowed "considerable improvement". ,,,<br />

the ,-aat + 3 of those w cough saw the condition disappear + tongues<br />

cleared up ; hearts not discussed in the paper//THENs diff . cigs given<br />

to patients w/glycerine as hygroscopic agent & in 80% of them congestion<br />

returned to larynx & pharynx & patients refused to smoke them<br />

anymore +"The glycerine cigs produced an irritation in the respiratory<br />

tract which is notably absent in the diethylene ones"//,at~ :end it says<br />

"This research was made possible thru a grant by <strong>PM</strong> & Co Ltd ._Inc ."<br />

http://legacy.library.ucsf.edu/tid/fmw44c00/pdf

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