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3rd International Congress 3rd International of Nuclear Congress Medicine of Nuclear & 15th Medicine Iranian Annual & 15th Iranian Congress Annual of Nuclear Congress Medicine of Nuclear Medicine Shahid Beheshti Shahid Beheshti University University of Medical Sciences of Medical 19-21 Sciences May 201119-21 May 2011 CME Lectures 34
3rd International Congress of of Nuclear Medicine & & 15th 15th Iranian Annual Annual Congress of Congress of Nuclear Medicine Shahid Beheshti Shahid Beheshti University University of Medical of Medical Sciences Sciences 19-21 19-21 May May 2011 NON-FDG PET TRACERS IN ONCOLOGY Mohsen Farsad (Italy) Nuclear Medicine Department, PET Unit, Policlinico S. Orsola-Malpighi, Bologna Educational Objectives: To delineate the appropriate clinical indications To help the imaging specialists to interpret correctly the images, avoiding pitfalls To get an insight on current status and future perspectives of NON FDG PET tracers Summery: [(18)F]-fluoro-2-deoxy-D-glucose (FDG) is the most frequently used radiopharmaceutical for clinical positron emission tomography (PET). However, FDG cannot be used for all cancer types, either because the abnormal tissue does not concentrate it, or because the tissues under investigation demonstrate high physiological glucose uptake. Consequently, alternative PET tracers have been produced and introduced into clinical practice. The most important NON FDG compounds in routine practice are 11 C-choline and 18 F-choline, mainly for the evaluation of prostate cancer; 11 C-methionine and 18 F-FET for brain tumours; 18 F-DOPA and 68 Ga-DOTA-PEPTIDES for neuroendocrine tumours. The lecture will highlight the major clinical applications of the above mentioned PET tracers in Oncology. Key Words: 11 C-choline; 18 F-choline; 18 F-DOPA; 11 C-methionine; 18 F-FET; 68 Ga-DOTA-NOC; 68 Ga-DOTA-TOC; PET-CT Imaging 35
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