Tierärztliche Hochschule Hannover Vergleichende Studie zur

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Publikation 2 SaO 2 [%] 105 100 95 90 85 80 a ab b a a a a a a a ab ab ab b ab a b INH INJ EPI p a CO 2 [mmHg] 80 75 70 65 60 55 50 a b a a a b a b a b a ab INH INJ EPI 75 70 0 -60 -30 0 b b 15 b 30 b 45 65 group effect: p = 0.0118 time effect: p = 0.1120 time x group effect: p = 0.0052 95 125 185 365 45 40 35 0 -60 c -30 0 b c 15 c 30 c 45 b 65 group effect: p = 0.0013 time effect: p < 0.0001 time x group effect: p < 0.0001 95 125 185 365 Time relative to start of operation [min] Time relative to start of the operation [min] arterial pH 7,45 7,40 7,35 7,30 7,25 7,20 0,00 -60 a b -30 a 0 a b b b a 15 b a b 30 b a b 45 b a b 65 b 95 a a b 125 ab 185 INH INJ EPI group effect: p = 0.0036 time effect: p < 0.0001 time x group effect: p < 0.0001 a b a b 365 ab Pulmonary Shunt [%] 45 40 35 30 25 20 15 10 5 0 -60 -30 b 0 a b 15 a b b 30 45 65 time effect: p = 0.0773 group effect: p = 0.0135 time x group effect: p = 0.0808 95 125 INH INJ EPI 185 365 Time relative to start of the operation [min] Time relative to start of the operation [min] Figure 3 Oxygen saturation (SaO 2 ), arterial partial pressure of carbon dioxide (p a CO 2 ), arterial pH and pulmonary shunt (Qs/Qt) of calves undergoing umbilical surgery under inhalation (INH; n=10), injection (INJ; n=10) and high volume caudal epidural anaesthesia (EPI; n=10). Baseline values (-60) are determined in the standing calf in the operating theatre. Between -60 and -30 min, calves were anaesthatised and positioned into dorsal recumbency (light grey underlay). The surgical period is marked by a dark grey underlay. Symbols with a dot differ significantly from baseline (p < 0.05). For each given point in time, significant differences between experimental groups are indicated by different letters. 52
Publikation 2 Tables dorsal recumbancy after surgery surgery sternal recumbancy or standing before surgery Group Stand Parameter (n) Stable - 60 min -30 min 0 min 15 min 30 min 45 min 65 min 95 min 125 min 185 min 365 min P-values Cortisol INH (10) 5.1 ± 5.1 10.2 ± 6.5 7.5 ± 4.1a 15.2 ± 9.7a 26.5 ± 7.7a 27.6 ± 7.1a 25.9 ± 8.5a 26.2 ± 7.0a 20.1 ± 8.2 10.4 ± 7.0 6.2 ± 4.3 3.5 ± 1.7 group 0.3577 [ng ml -1 ] INJ (10) 6.8 ± 5.1 10.7 ± 6.0 19.8 ± 13.7b 22.3 ± 10.1b 22.1 ± 11.7ab 25.9 ± 10.2ab 25.5 ± 11.3a 26.1 ± 13.5ab 23.3 ± 11.1 10.6 ± 5.6 8.1 ± 4.3 3.6 ± 2.3 time
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Tierärztliche Hochschule Hannover
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Meinen Eltern
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Abkürzungsverzeichnis A.a. a Abb.
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p a CO 2 arterieller Kohlendioxidpa
Page 10 and 11: Einleitung der geringe Wert des Ein
Page 12 and 13: Einleitung Naturgemäß können Tie
Page 14 and 15: Einleitung abdominalchirurgische Ei
Page 16 and 17: Einleitung Im Rahmen von Studien zu
Page 18 and 19: Literatur ENDENBURG, N., HARDIE, E.
Page 20 and 21: Literatur MATHEWS, K. A. (2000) Pai
Page 22 and 23: Literatur RINGS, D. M. & MUIR, W. W
Page 24 and 25: Publikation 1 Abstract The study de
Page 26 and 27: Publikation 2 Abstract Objective To
Page 28 and 29: Publikation 2 Introduction Abdomina
Page 30 and 31: Publikation 2 water. Daily clinical
Page 32 and 33: Publikation 2 solution (37°C) at a
Page 34 and 35: Publikation 2 Measured parameters A
Page 36 and 37: Publikation 2 • alveolar oxygen t
Page 38 and 39: Publikation 2 set intraoperative pr
Page 40 and 41: Publikation 2 Qs/Qt (Fig. 3) in com
Page 42 and 43: Publikation 2 whether movement by t
Page 44 and 45: Publikation 2 resulting from proced
Page 46 and 47: Publikation 2 As in this study the
Page 48 and 49: Publikation 2 can definitely be reg
Page 50 and 51: Publikation 2 REFERENCES: Amory H,
Page 52 and 53: Publikation 2 Hogan QH, Stadnicka A
Page 54 and 55: Publikation 2 Meyer H, Starke A, Ke
Page 56 and 57: Publikation 2 Stanek B, Schwarz M,
Page 58 and 59: Publikation 2 Figures b 30 INH INJ
Page 62 and 63: Publikation 2 Group Stand Parameter
Page 64 and 65: Publikation 3 Publikation 3: Case r
Page 66 and 67: Publikation 3 rates, as well as bod
Page 68 and 69: Publikation 3 On sagittal and trans
Page 70 and 71: Publikation 3 formation of internal
Page 72 and 73: Publikation 3 blood flow 15 caused
Page 74 and 75: Publikation 3 flushing with hepatin
Page 76 and 77: Publikation 3 References: 1. Offing
Page 78 and 79: Publikation 3 70
Page 80 and 81: Publikation 3 Figure 2: Spinal cord
Page 82 and 83: Publikation 3 Figure 4: Arteria spi
Page 84 and 85: Übergreifende Diskussion Basierend
Page 86 and 87: Übergreifende Diskussion Basalwert
Page 88 and 89: Übergreifende Diskussion diesen Ti
Page 90 and 91: Übergreifende Diskussion Aortenpun
Page 92 and 93: Literatur KOCHS, E., BLANC, I., WER
Page 94 and 95: Zusammenfassung Jennifer Offinger (
Page 96 and 97: Zusammenfassung signifikanter Ansti
Page 98 and 99: Summary applied to monitor intraope
Page 100 and 101: Danksagungen An erster Stelle gilt
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Tierärztliche Hochschule Hannover Vergleichende Studie zur

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