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Tierärztliche Hochschule Hannover Vergleichende Studie zur

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Publikation 3<br />

On sagittal and transverse T1-weighted images (TR: 330 ms, TE 12 ms, slice<br />

thickness 3 mm) the described intramedullary lesion was normointense, while the<br />

muscular abnormality showed a mildly hypointense signal. After the administration of<br />

contrast-medium m (0.2 mmol/kg IV) no pathological enhancement of the spinal cord<br />

but missing physiological enhancement of the described paraspinal muscle and the<br />

body of the fifth lumbar vertebra was present. Gradient-echo magnetic resonance<br />

images (TR: 880 ms, TE 26 ms, slice thickness 3 mm) in transverse plane provided<br />

an hyperintensity of the changed spinal cord parenchyma, whereas the described<br />

paraspinal musculature showed an inhomogeneous hyperintens signal with multifocal<br />

hypointense areas as an indication of necrosis within this muscle group. Altogether,<br />

MRI findings supported the clinical differential diagnosis and indicated profound focal<br />

ischemic necrosis, particularly of the grey matter in the caudal lumbar and cranial<br />

sacral segments of the spinal column.<br />

Despite intense physical therapy and continuation of medication for one week,<br />

the calf’s ability to stand did not improve. In consideration of the poor prognosis and<br />

in consent of animal welfare, the calf was thus euthanized and submitted for postmortem<br />

examination.<br />

Pathological examination revealed a mild to moderate, focal subacute<br />

hematoma with necrosis, mineralization, resorptive lymphohistiocytic inflammation,<br />

hemosiderosis and granulation-tissue formation within the muscular and<br />

retroperitoneal tissues along the puncture channel and focally surrounding the<br />

abdominal aorta. On the left side of the abdominal aorta, on the level of the 4 th<br />

60

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