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Henry Baird Favill, AB, MD, LL.D., 1860-1916, a ... - University Library

Henry Baird Favill, AB, MD, LL.D., 1860-1916, a ... - University Library

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io8 HENRY BAIRD FAVI<strong>LL</strong><br />

Delivered to Alumni of Rush Medical College, June, 1897.<br />

Printed, Intercollegiate Medical Journal, July, 1897.<br />

IN<br />

TOXIC CORRELATION<br />

regard to this somewhat startHng title I wish to<br />

explain that my idea is to suggest the fact, that there<br />

exist in our clinical experience many conditions and<br />

combinations of conditions, whose origin and sequence<br />

bear to each other very close relation, and that not in haphazard<br />

ways but in ways most methodical.<br />

We are now in the era of observation of toxic phenomena,<br />

and see with a distinctness heretofore impossible<br />

much of the truth which unlocks obscure situations.<br />

It is noteworthy that the legitimate fruit of the most<br />

advanced research is a well-demonstrated humoral pathology,<br />

the limits of which one dare not at this time suggest.<br />

After all the satisfactory light shed by cellular pathology,<br />

the query was bound to come, Why has a cell a<br />

pathology? The answer has come provisionally and is<br />

furnished by chemists and biologists as follows: The perverted<br />

cell has three main sources of its degeneracy, (a)<br />

nutritive supply corresponding to environment, (b) its<br />

innervation, constituting its functional experience, and<br />

(c) its tropic control; all evolved under the potential of<br />

its<br />

heredity.<br />

Therefore when we regard morbid states as the aggregate<br />

reaction of the molecular body subject to those influences,<br />

Its<br />

need we be surprised that the simple pathologic<br />

conditions take multiple forms, or that various unlike<br />

manifestations may trace a common origin?<br />

I wish to confine my comments to conditions which are<br />

explained by toxic materials in the circulatory blood, and<br />

to define toxic in such terms as to imply material which<br />

is noxious, either in kind or in relative amount.<br />

It is not possible, even if time permitted, to define the

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