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Innovation in European healthcare – what can Sweden learn? - LIF

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The Government’s fund<strong>in</strong>g has also contributed to the<br />

establishment of NIHR’s two Translational Research<br />

Partnerships (TRPs)<br />

• TRPs offer “an efficient and effective way for companies to work with some of the UK’s lead<strong>in</strong>g translational research<br />

experts” --Dr. Allison Jeynes-Ellis, Medical and <strong>Innovation</strong> Director at the Association of the British Pharmaceutical<br />

Industry (ABPI)<br />

• TRPs facilitate collaborative efforts between the NHS, university cl<strong>in</strong>ical researchers, and life science companies <strong>in</strong><br />

certa<strong>in</strong> fields of cl<strong>in</strong>ical <strong>in</strong>terest and unmet cl<strong>in</strong>ical need.<br />

• The rationale beh<strong>in</strong>d TRPs is that they will attract <strong>in</strong>vestment from pharmaceutical companies, by provid<strong>in</strong>g access to<br />

a unique network of world-class research expertise, <strong>in</strong>frastructure, and cohorts for well-characterised patients for<br />

early stage research.<br />

• There are currently two TRPs <strong>in</strong> operation:<br />

– Inflammatory Respiratory Disease - <strong>in</strong>clud<strong>in</strong>g asthma, allergy, COPD, cystic fibrosis, acute lung <strong>in</strong>jury,<br />

respiratory <strong>in</strong>fection<br />

– Jo<strong>in</strong>t and Related Inflammatory diseases - <strong>in</strong>clud<strong>in</strong>g, rheumatoid arthritis, osteoarthritis, synovitis<br />

• A key feature to facilitate partnerships is the new set-up for a s<strong>in</strong>gle legal agreement for collaboration with TRPs, thus<br />

cutt<strong>in</strong>g red-tape and elim<strong>in</strong>at<strong>in</strong>g the need for companies hav<strong>in</strong>g to negotiate with NHS Trusts and universities<br />

<strong>in</strong>dividually. The NIHR Office for Cl<strong>in</strong>ical Research Infrastructure (NOCRI) provides a s<strong>in</strong>gle po<strong>in</strong>t of access for<br />

companies to carry out research with TRPs.<br />

• TRPs build on the £800 million <strong>in</strong>vestment committed to the BRCs and BRUs. The launch of the two TRPs is<br />

supported by the allocation of £1.3 million <strong>in</strong> develop<strong>in</strong>g collaborations with <strong>in</strong>dustry, via NOCRI.<br />

• The activities of TRPs span a range of translational research, <strong>in</strong>clud<strong>in</strong>g pre-cl<strong>in</strong>ical models, exploratory trials, phase I<br />

and phase II proof of concept cl<strong>in</strong>ical drug trials and other studies of medical technology and diagnostic applications.<br />

191

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