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an investigation into the antibacterial activities of medicinal plants ...

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Fur<strong>the</strong>r testing on <strong>the</strong> pl<strong>an</strong>t extracts could be done on <strong>an</strong>ti-inflammatory activity,<br />

<strong>an</strong>tifungal activity, toxicity studies, <strong>an</strong>ti-ageing effects <strong>an</strong>d its effect on keritinocytes <strong>of</strong><br />

<strong>the</strong> skin to assess <strong>the</strong> full spectrum <strong>of</strong> <strong>the</strong> skin <strong>an</strong>d <strong>the</strong> benefits <strong>of</strong> <strong>the</strong>se pl<strong>an</strong>t<br />

extracts. Some <strong>medicinal</strong> pl<strong>an</strong>ts such as Centella asiatica have wound-healing<br />

properties <strong>an</strong>d assist in retracting <strong>the</strong> wound by facilitating <strong>the</strong> development <strong>of</strong><br />

normal connective tissue.<br />

Medicinal pl<strong>an</strong>ts used for treating burn wounds, abscesses <strong>an</strong>d boils, may contain<br />

<strong>an</strong>algesic activity that assist in alleviating <strong>the</strong> pain (V<strong>an</strong> Wyk & Gericke, 2000). In<br />

vivo testing <strong>of</strong> <strong>the</strong> different pl<strong>an</strong>t extracts done on rats may be helpful in assessing<br />

<strong>the</strong> wound healing properties <strong>of</strong> <strong>the</strong> pl<strong>an</strong>ts such as increasing <strong>the</strong> tissue<br />

keratinisation. The high <strong>an</strong>tibacterial activity against a wide r<strong>an</strong>ge <strong>of</strong> pathogens in<br />

this study makes M. major a promising pl<strong>an</strong>t for fur<strong>the</strong>r <strong>investigation</strong> <strong>into</strong> <strong>the</strong> woundhealing<br />

properties <strong>an</strong>d <strong>the</strong> above-mentioned studies.<br />

The <strong>medicinal</strong> pl<strong>an</strong>ts selected in this study may have additional properties that are<br />

beneficial to <strong>the</strong> skin when treating wound infections such as wound-healing<br />

properties <strong>an</strong>d pain relief. The ethnobot<strong>an</strong>ical approach to selecting pl<strong>an</strong>ts for<br />

scientific <strong>investigation</strong> is subst<strong>an</strong>tiated as <strong>the</strong> traditional uses <strong>of</strong> <strong>the</strong>se pl<strong>an</strong>ts in<br />

treating bacterial wound infections are justified.<br />

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