The obesogenic effects of polyunsaturated fatty acids are dependent ...
The obesogenic effects of polyunsaturated fatty acids are dependent ...
The obesogenic effects of polyunsaturated fatty acids are dependent ...
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nifedipine supplementation (1 g/kg) diet for 4 weeks. (A) Expressions <strong>of</strong> Acox1 (acyl-CoA oxidase<br />
1), Cpt1a (carnitine palmitoyltransferase 1a), Cpt2 (carnitine palmitoyltransferase 2), Hmgcs2 (3-<br />
hydroxy-3-methylglutaryl-Coenzyme A synthase 2), Srebf1 (sterol regulatory element binding<br />
transcription factor 1), Scd1 (stearoyl-Coenzyme A desaturase 1), Acaca (acetyl-Coenzyme A<br />
carboxylase alpha), Fasn (<strong>fatty</strong> acid synthase), Crem (cAMP responsive element modulator), Pde4c<br />
(phosphodiesterase 4C, cAMP specific), Ppargc1a (peroxisome proliferator-activated receptor<br />
gamma, coactivator 1 alpha), Pck1 (phosphoenolpyruvate carboxykinase 1, cytosolic), Gpt1a<br />
(glutamic pyruvic transaminase 1a), Got1 (glutamate oxaloacetate transaminase 1, soluble), Agxt<br />
(alanine-glyoxylate aminotransferase) and Cps1 (carbamoyl-phosphate synthetase 1) were measured<br />
in liver using RT-qPCR and normalized to Tbp (TATA-box binding protein). (B) Intraperitoneal<br />
glucose tolerance test and insulin glucose tests were performed. Data <strong>are</strong> presented as mean ± SEM.<br />
Different small letters denote significant differences (P
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