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The Exploit: A Theory of Networks - asounder

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Nodes 51<br />

be it in the living cell, in a petri dish or test tube, or, more recently, in a<br />

computer.<br />

<strong>The</strong> widespread use <strong>of</strong> computer databases (GenBank), Web - based<br />

gene - finding algorithms (BLAST), and automated genome sequencing<br />

computers demonstrates the principle <strong>of</strong> base pair complementarity<br />

in silico, in addition to the in vitro and in vivo.<br />

In short, the increasing integration <strong>of</strong> cybernetics and biology has resulted<br />

in an informatic view <strong>of</strong> life that is also a view <strong>of</strong> life as a network (“biological<br />

control”).<br />

But it is when we see biotechnology in its instrumental, yet nonmedical,<br />

nonbiological context, that the “protocols” <strong>of</strong> biological control<br />

become the most evident. One such example is the nascent field<br />

<strong>of</strong> DNA computing, or biocomputing. 20<br />

<strong>The</strong> actual design and construction <strong>of</strong> a computer made <strong>of</strong> DNA takes<br />

these protocols or biological control into a whole new field <strong>of</strong> concern beyond<br />

the traditional distinctions <strong>of</strong> biology and technology.<br />

While DNA computing is so new that it has yet to find its “killer<br />

app,” it has been used in a range <strong>of</strong> contexts from cryptography to<br />

network routing or navigation problems to the handheld detection <strong>of</strong><br />

biowarfare agents. <strong>The</strong> techniques <strong>of</strong> DNA computing were developed<br />

in the mid - 1990s by Leonard Adleman as a pro<strong>of</strong> - <strong>of</strong> - concept<br />

experiment in computer science. 21 <strong>The</strong> concept is that the combinatorial<br />

possibilities inherent in DNA (not one but two sets <strong>of</strong> binary<br />

pairings in parallel, A - T, C - G) could be used to solve specific types<br />

<strong>of</strong> calculations. One famous one is the so - called traveling salesman<br />

problem (also more formally called a “directed Hamiltonian path”<br />

problem): imagine a salesman who must go through five cities. <strong>The</strong><br />

salesman can visit each city only once and cannot retrace his steps.<br />

What is the most efficient way to visit all five cities? In mathematical<br />

terms, the types <strong>of</strong> calculations are called “NP complete” problems,<br />

or “nonlinear polynomial” problems, because they involve a large

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