First 11 pages of thesis. - OPUS - Universität Würzburg
First 11 pages of thesis. - OPUS - Universität Würzburg
First 11 pages of thesis. - OPUS - Universität Würzburg
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3.3 nNOS contributes little to vascular nitric oxide production<br />
Determination <strong>of</strong> vascular nitric oxide production using Fe-(DETC)2<br />
showed no significant difference between apoE ko and apoE/nNOS dko animals<br />
(2471±189 AU/µg protein, n=16 vs. 2293±124 AU/µg protein, n=17, p=0.43,<br />
Figure 10). However, a trend towards reduction <strong>of</strong> vascular nitric oxide<br />
production (7%) was observed in apoE/nNOS dko animals suggesting that<br />
nNOS may have a minor contribution.<br />
Figure 10. Contribution <strong>of</strong> vascular nitric oxide by nNOS: ESR measurements <strong>of</strong> vascular<br />
nitric oxide levels using Fe-(DETC)2 showed no significant difference between apoE ko and<br />
apoE/nNOS dko animals (NS).<br />
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