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Technical Guidelines for Integrated Disease Surveillance ... - PHRplus

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Cholera may cause severe dehydration in only a few hours. The case fatality rate(CFR) may exceed 50% in untreated patients with severe dehydration. If patientspresent at the health facility and correct treatment is received, the CFR is usually lessthan 1%. In Ghana the CFR <strong>for</strong> 2000 is currently an average of 2.7%. At least 90% ofthe cases are mild, and they remain undiagnosed. Risk factors: eating or drinking of contaminated foods such as uncooked seafood orshellfish from estuarine waters, lack of continuous access to safe water and foodsupplies, attending large gatherings of people including ceremonies such as weddingsor funerals, contact with persons who died of cholera. Other enteric diseases may cause watery diarrhoea, especially in children less than 5years of age.<strong>Surveillance</strong> goal Detect and respond promptly and appropriately to cases and outbreaks of waterdiarrhoea promptly. Immediately report case-based cases (case-based reporting) and deaths when anoutbreak is suspected.Investigate and respond to suspected cases within 48 hours.Case definitionSuspected case:In a patient age 5 years or more, severe dehydration or death from acute watery diarrhoea(rice water stool).If there is a cholera epidemic, a suspected case is a person age 5 years or more with acutewatery diarrhoea, with or without vomiting.Confirmed case:A suspected case in which Vibrio cholerae O1 or O139 has been isolated in the stool.Respond to alertthresholdRespond to epidemicthresholdIf a single case is suspected: Report case-based in<strong>for</strong>mation immediately. Manage and treat the case according to national guidelines. Enhance strict handwashing and isolating procedures. Conduct case-based investigation to identify similar cases not previously reported andconfirm the outbreak. Obtain stool specimens from 5 patients within 5 days of onset of acute waterydiarrhoea, and be<strong>for</strong>e antibiotic treatment is started. See laboratory guidelines <strong>for</strong>in<strong>for</strong>mation on how to prepare, store and transport specimens. To confirm an outbreak,collect stool specimens to be transported to the lab in Cary-Blair medium. Mobilise community early to enable rapid case detection and treatment.Survey the availability of safe drinking water.If a suspected case is confirmed: Establish treatment centre in locality where cases occur. Treat cases onsite rather thanasking patients to go to standing treatment centres elsewhere. Strengthen management and treatment of cases. Work with community leaders to limit the number of funerals or other large gatherings<strong>for</strong> ceremonies or other reasons, especially during an epidemic. Reduce sporadic and outbreak-related cases through continuous access to safe water.Promote safe preparation of food (especially seafood, fruits and vegetables). Promotesafe disposal of human waste.Analyse and interpretdataTime:Place:Graph weekly cases and deaths and construct an epidemic curve duringoutbreaks. Report case-based in<strong>for</strong>mation immediately and summaryin<strong>for</strong>mation weekly and monthly <strong>for</strong> routine surveillance.Plot the location of case by community/village.Section 9: Summary <strong>Guidelines</strong> <strong>for</strong> Specific Priority <strong>Disease</strong>s and Conditions91

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