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The MMWR series of publications is published by the<br />

Epidemiology Program Office, Centers for Disease<br />

Control and Prevention (CDC), U.S. Department of<br />

Health and Human Services, Atlanta, GA 30333.<br />

SUGGESTED CITATION<br />

Centers for Disease Control and Prevention. Sexually<br />

transmitted diseases treatment guidelines 2002.<br />

MMWR 2002;51(No. RR-6):[inclusive page<br />

numbers].<br />

Centers for Disease Control and Prevention<br />

David W. Fleming, M.D.<br />

Acting Director<br />

Julie L. Gerberding, M.D.<br />

Acting Deputy Director for Science and Public Health<br />

Dixie E. Snider, Jr., M.D., M.P.H.<br />

Associate Director for Science<br />

Epidemiology Program Office<br />

Stephen B. Thacker, M.D., M.Sc.<br />

Director<br />

Office of Scientific and Health Communications<br />

John W. Ward, M.D.<br />

Director<br />

Editor, MMWR Series<br />

Suzanne M. Hewitt, M.P.A.<br />

Managing Editor<br />

Rachel J. Wilson<br />

Project Editor<br />

Malbea A. Heilman<br />

Beverly J. Holland<br />

Visual Information Specialists<br />

Michele D. Renshaw<br />

Erica R. Shaver<br />

Information Technology Specialists<br />

MMWR<br />

CONTENTS<br />

Introduction ..................................................................................................... 1<br />

Clinical Prevention Guidelines .......................................................................... 2<br />

Prevention Messages .................................................................................... 2<br />

Prevention Methods ...................................................................................... 3<br />

STD/HIV Prevention Counseling .................................................................... 4<br />

Partner Notification ...................................................................................... 4<br />

Reporting and Confidentiality ....................................................................... 4<br />

Special Populations .......................................................................................... 5<br />

Pregnant Women ......................................................................................... 5<br />

Adolescents .................................................................................................. 6<br />

Children ....................................................................................................... 7<br />

Men Who Have Sex with Men ....................................................................... 7<br />

HIV Infection: Detection, Counseling, and Referral ........................................... 7<br />

Detection of HIV Infection: Diagnostic Testing ............................................... 8<br />

Counseling for Patients with HIV Infection and Referral to Support Services ... 9<br />

Management of Sex Partners and Injection-Drug Partners ........................... 10<br />

Special Considerations ............................................................................... 10<br />

Diseases Characterized by Genital Ulcers ....................................................... 11<br />

Management of Patients Who Have Genital Ulcers ..................................... 11<br />

Chancroid .................................................................................................. 11<br />

Genital Herpes Simplex Virus Infections ...................................................... 12<br />

Granuloma Inguinale (Donovanosis) .......................................................... 17<br />

Lymphogranuloma Venereum ..................................................................... 18<br />

Syphilis ...................................................................................................... 18<br />

Congenital Syphilis ........................................................................................ 26<br />

Evaluation and Treatment of Infants in the First Month of Life ..................... 26<br />

Evaluation and Treatment of Older Infants and Children ............................. 28<br />

Follow-Up .................................................................................................. 28<br />

Special Considerations ............................................................................... 28<br />

Management of Patients Who Have a History of Penicillin Allergy ................... 28<br />

Recommendations ...................................................................................... 29<br />

Penicillin Allergy Skin Testing ...................................................................... 29<br />

Diseases Characterized by Urethritis and Cervicitis ......................................... 30<br />

Management of Male Patients Who Have Urethritis .................................... 30<br />

Etiology ...................................................................................................... 30<br />

Confirmed Urethritis ................................................................................... 30<br />

Management of Patients Who Have Nongonococcal Urethritis .................... 31<br />

Management of Patients Who Have Mucopurulent Cervicitis (MPC) ............. 32<br />

Chlamydial Infections ................................................................................. 32<br />

Gonococcal Infections ................................................................................ 36<br />

Diseases Characterized by Vaginal Discharge ................................................. 42<br />

Management of Patients Who Have Vaginal Infections ................................ 42<br />

Bacterial Vaginosis ..................................................................................... 42<br />

Trichomoniasis ........................................................................................... 44<br />

Vulvovaginal Candidiasis ............................................................................ 45<br />

Pelvic Inflammatory Disease ........................................................................... 48<br />

Diagnostic Considerations .......................................................................... 48<br />

Treatment .................................................................................................. 49<br />

Follow-Up .................................................................................................. 51<br />

Management of Sex Partners ...................................................................... 51<br />

Prevention .................................................................................................. 51<br />

Special Considerations ............................................................................... 51<br />

Epididymitis ................................................................................................... 52<br />

Diagnostic Considerations .......................................................................... 52<br />

Treatment .................................................................................................. 52<br />

Follow-Up .................................................................................................. 53<br />

Management of Sex Partners ...................................................................... 53<br />

Special Considerations ............................................................................... 53<br />

Human Papillomavirus Infection ..................................................................... 53<br />

Genital Warts ............................................................................................. 53<br />

Subclinical Genital HPV Infection (Without Exophytic Warts) ........................ 57<br />

Cervical Cancer Screening for Women Who Attend STD Clinics<br />

or Have a History of STDs ............................................................................ 57<br />

Recommendations ...................................................................................... 58<br />

Special Considerations ............................................................................... 59<br />

Vaccine Preventable STDs .............................................................................. 59<br />

Hepatitis A ................................................................................................. 59<br />

Hepatitis B ................................................................................................. 61<br />

Hepatitis C .................................................................................................... 64<br />

Sexual Activity ............................................................................................ 65<br />

Diagnosis and Treatment ............................................................................ 65<br />

Prevention .................................................................................................. 65<br />

Postexposure Follow-Up ............................................................................. 66<br />

Proctitis, Proctocolitis, and Enteritis ................................................................. 66<br />

Treatment .................................................................................................. 67<br />

Follow-Up .................................................................................................. 67<br />

Management of Sex Partners ...................................................................... 67<br />

Ectoparasitic Infections ................................................................................... 67<br />

Pediculosis Pubis ........................................................................................ 67<br />

Scabies ...................................................................................................... 68<br />

Sexual Assault and STDs ................................................................................ 69<br />

Adults and Adolescents .............................................................................. 69<br />

Evaluation for Sexually Transmitted Infections ............................................. 69<br />

Sexual Assault or Abuse of Children ........................................................... 71<br />

References ..................................................................................................... 74<br />

Abbreviations Used in This Publication ........................................................... 77

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